Results 1 to 10 of about 146,670 (267)
RET Regulates Human Medullary Thyroid Cancer Cell Proliferation through CDK5 and STAT3 Activation
Biomolecules, 2021 Medullary thyroid cancer (MTC) is a neuroendocrine tumor that arises from the parafollicular C-cells, which produces the hormone calcitonin. RET is a transmembrane receptor protein-tyrosine kinase, which is highly expressed in MTC.
Chia-Herng Yue +8 more
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Genetic susceptibility to hereditary non-medullary thyroid cancer
Hereditary Cancer in Clinical Practice, 2022 Non-medullary thyroid cancer (NMTC) is the most common type of thyroid cancer. With the increasing incidence of NMTC in recent years, the familial form of the disease has also become more common than previously reported, accounting for 5–15% of NMTC ...
Tina Kamani +3 more
doaj +2 more sources
Cancer control : journal of the Moffitt Cancer CenterBACKGROUND: Medullary thyroid cancer, a tumor of the parafollicular C cells, accounts for approximately 10% of all thyroid malignancies. An estimated 75% of cases are sporadic, and the remaining 25% are familial. METHODS: The author reviews the clinical features and diagnostic tests for this entity, as well as the surgical treatment of recurrent or ...
Ramos Santillan V +3 more
europepmc +7 more sources
Changing the paradigm: lobectomy for sporadic medullary thyroid cancer [PDF]
European Thyroid JournalObjectives: Total thyroidectomy is the treatment of choice for medullary thyroid cancer (MTC), although the sporadic forms are usually monocentric. Aim of the present study was to evaluate i) the performance of calcitonin (Ct) levels, ultrasound scans ...
Marina Lugaresi +5 more
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Medullary thyroid cancer: epidemiology
Mìžnarodnij Endokrinologìčnij Žurnal, 2023 Epidemiology of medullary thyroid cancer is presented in the literature review. Thyroid cancer is the most common form of endocrine oncological pathology. It accounts for 96–97 % of all malignant tumors of endocrine organs. According to the Surveillance,
S. Rybakov
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Medullary Thyroid Cancer: Updates and Challenges
Endocrine reviews, 2023 A personalized approach to the management of medullary thyroid cancer (MTC) presents several challenges; however, in the past decade significant progress has been made in both diagnostic and treatment modalities. Germline rearranged in transfection (RET)
M. Gild +3 more
semanticscholar +1 more source
Biomedicines, 2023 Medullary thyroid cancer originates from parafollicular C-cells in the thyroid. Despite successful thyroidectomy, localizing remnant cancer cells in patients with elevated calcitonin and carcinoembryonic antigen levels remains a challenge.
Hyeon Jeong Lee +9 more
doaj +1 more source
Innovations in the systemic treatment of medullary thyroid cancer with kinase inhibitors
Journal of Education, Health and Sport, 2023 Introduction: Medullary thyroid carcinoma is a primary thyroid neoplasm originating from thyroid C cells. It can be familial or sporadic. The familial form is associated with multiple endocrine neoplasia (MEN) syndrome types 2A and 2B and is caused by a
Wiktoria Lipczyńska +7 more
doaj +1 more source
Alcohol abuse as a risk factor for developing thyroid cancer [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2021 Introduction/Objective. Alcohol abuse influence on developing thyroid cancer is controversial. While some studies consider it a protective factor, others deny any impact on thyroid cancer.
Kalezić Nevena +6 more
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Human Pathology Reports, 2022 Tumour-to-tumour metastasis is a rare incidence. Metastasis from colorectal cancer to primary thyroid neoplasm is extremely rare. We report a case of metastatic rectal adenocarcinoma to a medullary thyroid carcinoma.
Mahmoud Elsayed +2 more
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