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Cancer control : journal of the Moffitt Cancer CenterBACKGROUND: Medullary thyroid cancer, a tumor of the parafollicular C cells, accounts for approximately 10% of all thyroid malignancies. An estimated 75% of cases are sporadic, and the remaining 25% are familial. METHODS: The author reviews the clinical features and diagnostic tests for this entity, as well as the surgical treatment of recurrent or ...
Ramos Santillan V +3 more
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Cabozantinib for progressive metastatic medullary thyroid cancer: a review [PDF]
Therapeutics and Clinical Risk Management, 2014 Joshua R Colombo, Richard O Wein Department of Otolaryngology, Head and Neck Surgery, Tufts Medical Center, Boston, MA, USA Abstract: Medullary thyroid cancer is uncommon and patients typically present with advanced disease.
Colombo JR, Wein RO
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Changing the paradigm: lobectomy for sporadic medullary thyroid cancer [PDF]
European Thyroid JournalObjectives: Total thyroidectomy is the treatment of choice for medullary thyroid cancer (MTC), although the sporadic forms are usually monocentric. Aim of the present study was to evaluate i) the performance of calcitonin (Ct) levels, ultrasound scans ...
Marina Lugaresi +5 more
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Targeted Therapy for Medullary Thyroid Cancer: A Review
Frontiers in Oncology, 2017 Medullary thyroid cancers (MTCs) constitute between 2 and 5% of all thyroid cancers. The 10-year overall survival (OS) rate of patients with localized disease is around 95% while that of patients with regional stage disease is about 75%.
S. R. Priya +6 more
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A Benign Medullary Thyroid Cancer [PDF]
Cureus, 2022 Metastatic dissemination occurs in up to 90% of patients with medullary thyroid cancer (MTC) greater than 4 cm in diameter, and elevated calcitonin levels of more than 500 pg/ml preoperatively have been shown to predict the failure to achieve biochemical remission. Herein, we present a patient with a large tumor and extremely elevated calcitonin level,
Pishdad, Reza +2 more
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Medullary thyroid cancer: epidemiology
Mìžnarodnij Endokrinologìčnij Žurnal, 2023 Epidemiology of medullary thyroid cancer is presented in the literature review. Thyroid cancer is the most common form of endocrine oncological pathology. It accounts for 96–97 % of all malignant tumors of endocrine organs. According to the Surveillance,
S. Rybakov
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Biomedicines, 2023 Medullary thyroid cancer originates from parafollicular C-cells in the thyroid. Despite successful thyroidectomy, localizing remnant cancer cells in patients with elevated calcitonin and carcinoembryonic antigen levels remains a challenge.
Hyeon Jeong Lee +9 more
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Medullary Thyroid Cancer Follow-Up Results: 20 Years of Experience in a Tertiary Center
Cerrahpaşa Medical Journal, 2023 Objective: The aim of our study was to present our experience with medullary thyroid cancer and to identify the characteristics of patients in relapse or remission.
Zehra Kara +3 more
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RET Regulates Human Medullary Thyroid Cancer Cell Proliferation through CDK5 and STAT3 Activation
Biomolecules, 2021 Medullary thyroid cancer (MTC) is a neuroendocrine tumor that arises from the parafollicular C-cells, which produces the hormone calcitonin. RET is a transmembrane receptor protein-tyrosine kinase, which is highly expressed in MTC.
Chia-Herng Yue +8 more
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Innovations in the systemic treatment of medullary thyroid cancer with kinase inhibitors
Journal of Education, Health and Sport, 2023 Introduction: Medullary thyroid carcinoma is a primary thyroid neoplasm originating from thyroid C cells. It can be familial or sporadic. The familial form is associated with multiple endocrine neoplasia (MEN) syndrome types 2A and 2B and is caused by a
Wiktoria Lipczyńska +7 more
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