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The goal in managing patients who have MTC is to detect and surgically remove disease at an early stage. Tumor marker-based biochemical screening and DNA-based genetic screening have created the opportunity for effective prophylactic surgery in patients at risk for hereditary MTC.
Y Nancy, You +3 more
openaire +4 more sources
Medullary thyroid cancer is rare, in 25 % of cases genetically determined (multiple endocrine neoplasia type 2), and should be treated by a specialized multidisciplinary team in the Cancer Center. In most cases, total thyroidectomy and at least central compartment lymph node dissection are required.
Barney Harrison, Bruno Carnaille
+5 more sources
Breast metastasis from medullary thyroid carcinoma: a report of a case
Background Metastasis to the breast is rare. We herein report a patient with metastatic medullary thyroid carcinoma to the breast for whom measuring the calcitonin level was an important clue to the correct diagnosis.
Yoko Omi +6 more
doaj +1 more source
the aim of the stydy was to analyze the detectability of medullary thyroid metastases in patients at treatment and diagnostic stages, to investigate the applicability of serum calcitonin level as predictor of possible presence of medullary thyroid ...
Volodymyr Palamarchuk +6 more
doaj +1 more source
Detection rate of FNA cytology in medullary thyroid carcinoma. a meta-analysis [PDF]
Background: The early detection of medullary thyroid carcinoma (MTC) can improve patient prognosis, because histological stage and patient age at diagnosis are highly relevant prognostic factors. As a consequence, delay in the diagnosis and/or incomplete
Anna, Crescenzi +10 more
core +1 more source
Effects of marital status on survival of medullary thyroid cancer stratified by age
Marital status has emerged as an important influence on several cancer outcomes, but its role in medullary thyroid cancer (MTC) remains unclear. This study was to explore the effects of marital status on the prognosis of MTC patients and to determine ...
Lei Ai +11 more
semanticscholar +1 more source
Abstract Background Medullary thyroid cancer (MTC) standard of care includes multikinase inhibitors (MKIs), which can exacerbate disease‐related diarrhea, primarily because of non‐RET kinase inhibition. We report diarrhea and other patient‐reported outcomes (PROs) with selpercatinib, a highly selective RET inhibitor, among patients with RET‐mutant MTC ...
Lori J. Wirth +10 more
wiley +1 more source
External radiotherapy of thyroid cancer [PDF]
Differentiated thyroid cancer comprises papillary, mixed papillary-follicular and follicular adenocarcinomas. They are mostly hormone-sensitive and respond to thyroid-stimulating hormone (TSH) suppression. The standard treatment is total thyroidectomy. I-
Dühmke, Eckhart, Pollinger, B.
core +1 more source
Risk Patterns of Distant Metastases in Follicular, Papillary and Medullary Thyroid Cancer
This study of 542 patients with follicular thyroid cancer, 366 patients with the follicular variant and 1452 patients with the classical variant of papillary thyroid cancer, and 819 patients with sporadic medullary thyroid cancer operated at a tertiary ...
A. Machens +3 more
semanticscholar +1 more source
Combination of medullary thyroid cancer and renal cell carcinoma in one patient
Patients who received treatment for the first malignant neoplasm remain in the group at increased risk of developing a second primary tumor throughout their later life.
Yuliya A. Dolinskaya +4 more
doaj +1 more source

