Results 31 to 40 of about 3,167,167 (225)

Patient‐Reported Outcomes with Selpercatinib Treatment Among Patients with RET‐Mutant Medullary Thyroid Cancer in the Phase I/II LIBRETTO‐001 Trial

The Oncologist, EarlyView., 2021
Abstract Background Medullary thyroid cancer (MTC) standard of care includes multikinase inhibitors (MKIs), which can exacerbate disease‐related diarrhea, primarily because of non‐RET kinase inhibition. We report diarrhea and other patient‐reported outcomes (PROs) with selpercatinib, a highly selective RET inhibitor, among patients with RET‐mutant MTC ...
Lori J. Wirth, Bruce Robinson, Valentina Boni, Daniel S.W. Tan, Caroline McCoach, Erminia Massarelli, Lisa M. Hess, Min‐Hua Jen, Jennifer Kherani, Elizabeth Olek, Vivek Subbiah   +10 more
wiley   +1 more source

External radiotherapy of thyroid cancer [PDF]

, 2001
Differentiated thyroid cancer comprises papillary, mixed papillary-follicular and follicular adenocarcinomas. They are mostly hormone-sensitive and respond to thyroid-stimulating hormone (TSH) suppression. The standard treatment is total thyroidectomy. I-
Pollinger, B., Dühmke, Eckhart
core   +1 more source

Breast metastasis from medullary thyroid carcinoma: a report of a case

Surgical Case Reports, 2021
Background Metastasis to the breast is rare. We herein report a patient with metastatic medullary thyroid carcinoma to the breast for whom measuring the calcitonin level was an important clue to the correct diagnosis.
Yoko Omi, Hidenori Kamio, Yusaku Yoshida, Kenta Masui, Tomoko Yamamoto, Yoji Nagashima, Takahiro Okamoto   +6 more
doaj   +1 more source

Vandetanib for the Treatment of Metastatic Medullary Thyroid Cancer [PDF]

, 2012
Medullary thyroid cancer (MTC) represents an aggressive form of thyroid malignancy. Some may occur spontaneously or can be associated with Multiple Endocrine Neoplasia syndromes, or Familial Medullary Thyroid Cancer syndrome.
Nils Degrauwe, Degrauwe, Nils, Julie Ann Sosa, Sosa, Julie Ann, Deshpande, Hari A, Hari A. Deshpande, Sanziana Roman, Roman, Sanziana   +7 more
core   +1 more source

Increasing incidence of thyroid cancer in shanghai, China, 1983-2007 [PDF]

, 2011
Increasing incidences of thyroid cancer were observed in some countries, like USA, UK, France, etc. Jointpoint regression was used to analyze the incidence of thyroid cancer in Shanghai, China, from 1983 to 2007.
Youxin Wang, Wei Wang
core   +1 more source

Advanced medullary thyroid cancer: pathophysiology and management [PDF]

, 2013
Carla Vaz Ferreira, Débora Rodrigues Siqueira, Lucieli Ceolin, Ana Luiza MaiaThyroid Section, Endocrine Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, BrazilAbstract: Medullary thyroid carcinoma (MTC) is a rare malignant ...
Ceolin L, Maia AL, Ferreira CV, Siqueira DR   +3 more
core   +2 more sources

A Case of Mixed Medullary and Follicular Cell Carcinoma of the Thyroid [PDF]

, 2011
A medullary thyroid carcinoma is a malignant tumor derived from the C-cells of the thyroid. Despite their distinct embryological origin, medullary thyroid carcinomas are exceptionally accompanied by a tumor derived from the follicular cells; this is ...
Ai Haraguchi, Takao Ando, Tatsuya Uga, Toshiro Usa, Kawakami, Atsushi, Uga, Tatsuya, Haraguchi, Ai, Tomayoshi Hayashi, Usa, Toshiro, Ikuko Ueki, Ueki, Ikuko, Imaizumi, Misa, Ando, Takao, Hayashi, Tomayoshi, Atsushi Kawakami, Horie, Ichiro, Misa Imaizumi, Ichiro Horie   +17 more
core   +1 more source

Preventive Transoral Endoscopic Thyroidectomy by Vestibular Approach in 6-Year-Old Patient with the High-Risk RET C634R Germline Mutation

Case Reports in Oncology, 2023
Aggressiveness and age of manifestation of medullary thyroid cancer depend on the risk level of germline RET mutations. For high-risk mutations, preventive thyroidectomy is recommended at young age.
Yury Panaseykin, Vyacheslav Polkin, Nataliya Severskaya, Pavel Isaev, Aleksey Iliyn, Alisa Plugar, Ekaterina Kupriyanova, Sergey Ivanov, Andrey Kaprin   +8 more
doaj   +1 more source

Role of Interleukin-18 in Thyroid tumorigenesis [PDF]

, 2016
Purpose: Although the significance of Interleukin-18 (IL-18) has been studied in pathogenesis of different cancers including, ovarian, gastric, breast, lung carcinoma and melanoma, its role in thyroid cancer- the most common endocrine malignancy has not ...
Gajjar, Kinjal; Division of Molecular Endocrinology, Department of Cancer Biology, The Gujarat Cancer & Research Institute (GCRI), Ahmedabad-380 016, India, Kobawala, Toral; Division of Molecular Endocrinology, Department of Cancer Biology, The Gujarat Cancer & Research Institute (GCRI), Ahmedabad-380 016, India, Patel, Girish; Division of Molecular Endocrinology, Department of Cancer Biology, The Gujarat Cancer & Research Institute (GCRI), Ahmedabad-380 016, India, Ghosh, Nandita; Division of Molecular Endocrinology, Department of Cancer Biology, The Gujarat Cancer & Research Institute (GCRI), Ahmedabad-380 016, India, Trivedi, Trupti; Division of Molecular Endocrinology, Department of Cancer Biology, The Gujarat Cancer & Research Institute (GCRI), Ahmedabad-380 016, India   +4 more
core   +2 more sources

Role of Twist1 transcription factor in thyroid tumor progression [PDF]

, 2011
Thyroid carcinomas are the most common endocrine tumors in humans, with a globally increasing incidence. Differentiated tumors, such as papillary (PTC) and follicular (FTC) thyroid cancers, are often curable with surgical resection and radiotherapy ...
Bencivenga, Tammaro Claudio
core   +1 more source