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Thyroid cancer is the malignant tumor that is increasing most rapidly in the world, mainly at the expense of sporadic papillary thyroid carcinoma. The somatic alterations involved in the pathogenesis of sporadic follicular cell derived tumors are well ...
María Sánchez-Ares +9 more
doaj +1 more source
Advanced medullary thyroid cancer: pathophysiology and management [PDF]
Carla Vaz Ferreira, Débora Rodrigues Siqueira, Lucieli Ceolin, Ana Luiza MaiaThyroid Section, Endocrine Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, BrazilAbstract: Medullary thyroid carcinoma (MTC) is a rare malignant ...
Ceolin L +3 more
core +2 more sources
Medullary thyroid cancer (MTC) is a neuroendocrine tumor that arises from the calcitonin (CT)-producing thyroid parafollicular C cells, accounting for 3–4% of all thyroid cancers [1, 2].
Martínez-Montoro, José Ignacio +17 more
core +1 more source
Medullary thyroid cancer: a little history
The literature review presents the history on the development of modern ideas about medullary thyroid cancer, which is a little more than fifty years.
S.Y. Rybakov
doaj +1 more source
Vandetanib for the Treatment of Metastatic Medullary Thyroid Cancer [PDF]
Medullary thyroid cancer (MTC) represents an aggressive form of thyroid malignancy. Some may occur spontaneously or can be associated with Multiple Endocrine Neoplasia syndromes, or Familial Medullary Thyroid Cancer syndrome.
Nils Degrauwe +12 more
core +1 more source
A Phase 2 Trial of the Multi-targeted Tyrosine Kinase Inhibitor Lenvatinib (E7080) in Advanced Medullary Thyroid Cancer (MTC) [PDF]
Positive results of phase 1 studies evaluating lenvatinib in solid tumors including thyroid cancer prompted a phase 2 trial in advanced medullary thyroid carcinoma (MTC)
Mccaffrey, Judith +60 more
core +1 more source
Aggressiveness and age of manifestation of medullary thyroid cancer depend on the risk level of germline RET mutations. For high-risk mutations, preventive thyroidectomy is recommended at young age.
Yury Panaseykin +8 more
doaj +1 more source
Role of Twist1 transcription factor in thyroid tumor progression [PDF]
Thyroid carcinomas are the most common endocrine tumors in humans, with a globally increasing incidence. Differentiated tumors, such as papillary (PTC) and follicular (FTC) thyroid cancers, are often curable with surgical resection and radiotherapy ...
Bencivenga, Tammaro Claudio
core +1 more source
Evaluation of Thyroid Nodules: Incidence and Distribution of Thyroid Cancer
Thyroid nodules are a common problem in clinical practice, they are usually benign; only about 5% of these nodules harbor malignancy. It is important to identify those that are likely to be malignant. The majority of thyroid cancers are papillary cancers,
Mehmet Fırat +3 more
doaj +2 more sources
We report a rare case of simultaneous medullary thyroid carcinoma on the left thyroid lobe with lymph node metastasis and papillary thyroid cancer on the right thyroid lobe.
Nidal Younes
doaj +1 more source

