Results 41 to 50 of about 3,167,167 (225)
Evaluation of Thyroid Nodules: Incidence and Distribution of Thyroid Cancer
Thyroid nodules are a common problem in clinical practice, they are usually benign; only about 5% of these nodules harbor malignancy. It is important to identify those that are likely to be malignant. The majority of thyroid cancers are papillary cancers,
Mehmet Fırat +3 more
doaj +2 more sources
We report a rare case of simultaneous medullary thyroid carcinoma on the left thyroid lobe with lymph node metastasis and papillary thyroid cancer on the right thyroid lobe.
Nidal Younes
doaj +1 more source
Medullary thyroid cancer is rare, in 25 % of cases genetically determined (multiple endocrine neoplasia type 2), and should be treated by a specialized multidisciplinary team in the Cancer Center. In most cases, total thyroidectomy and at least central compartment lymph node dissection are required.
Tanima Jana +2 more
+5 more sources
Current perspectives on the management of patients with advanced RET-driven thyroid cancer in Europe
The incidence of thyroid cancer is increasing worldwide with the disease burden in Europe second only to that in Asia. In the last several decades, molecular pathways central to the pathogenesis of thyroid cancer have revealed a spectrum of targetable ...
Rossella Elisei +6 more
doaj +1 more source
Genetics of medullary thyroid cancer: An overview
Medullary thyroid carcinoma (MTC) represents 3-5% of thyroid cancers. 75% is sporadic and 25% is the dominant component of the hereditary multiple endocrine neoplasia (MEN) type 2 syndromes. Three different subtypes of MEN2, such as MEN2A, MEN2B, and Familial MTC (FMTC) have been defined, based on presence or absence of hyperparathyroidism ...
Accardo, Giacomo +11 more
openaire +2 more sources
A Case of F-18 FDG PET-CT Detection of Sporadic Medullary Thyroid Carcinoma and Cervical Lymph Node Metastasis of Ovarican Cancer [PDF]
Medullary thyroid carcinoma (MTC) is derived from the parafollicular or C-cells. As surgical resection is the only curative therapy for MTC, the early diagnosis is important for the patient's survival.
Joo Wan Seo +5 more
doaj +1 more source
Expression of FAS/APO 1/CD 95 in thyroid tumors.
Using immunohistochemistry, Fas/Apo-1 protein expression was investigated in thyroid cancers of 67 patients. Thyroid biopsies from twenty eight patients with benign thyroid diseases were also examined.
Waldemar Balcerzak +5 more
doaj +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Pathogenesis of endocrine thyroid cancer [PDF]
This review aims to discuss the different genetic alterations that may come about and thus give rise to thyroid cancer. The importance of understanding the pathogenesis of this disease is in the use of these genetic alterations as prognostic markers and ...
Vassallo, Josanne, Mallia, Nicola
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