Results 41 to 50 of about 682,686 (266)

Histopathological and immunohistochemical features of thyroid carcinoma [PDF]

open access: yesArchive of Oncology, 2003
Thyroid-specific malignant tumors are derived from follicle cells (papillary and follicular carcinoma), and from parafollicular, calcitonin-producing C-cells (medullary carcinoma). The main criterion for diagnosis of papillary carcinoma is the occurrence
Tatić Svetislav B.
doaj   +1 more source

Medullary thyroid carcinoma with double negative calcitonin and CEA: a case report and update of literature review

open access: yesBMC Endocrine Disorders, 2019
Background Medullary thyroid carcinoma is a malignant uncommon and aggressive tumour of the parafollicular C cells. In about 75% of cases it is sporadic while, in case of RET mutation, it is associated to multiple endocrine neoplasia type 2 (25% of cases)
Claudio Gambardella   +11 more
doaj   +1 more source

A Diagnostic Dilemma: A Young Boy with Loss of Weight, Pulmonary Infiltrates and Cervical Lymphadenitis [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2013
Cervical lymphadenitis is a common finding in young adults in a country like India, where tuberculosis is endemic. We are presenting the case of a young boy who presented with low grade fever, dry cough, weight loss, and a cervical swelling. His chest X-
Asmita A. Mehta   +2 more
doaj   +1 more source

Calcitonin-secreting neuroendocrine neoplasms of the lung: a systematic review and narrative synthesis

open access: yesEndocrine Connections, 2021
Calcitonin-secreting neuroendocrine neoplasms of the lung are rare, with few cases reported in the literature. Differentiating between medullary th yroid carcinoma and an ectopic source of calcitonin secretion can represent a complex diagnostic conundrum
David C Llewellyn   +8 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Calcitonin-negative medullary thyroid carcinoma: the \u27triple-negative\u27 phenotype

open access: yes, 2020
Calcitonin-negative medullary thyroid carcinoma is a rare, poorly understood primary neuroendocrine carcinoma of the thyroid characterised by classic medullary thyroid carcinoma morphology without raised serum calcitonin.
Aspinall S, Johnson SJ, Murphy DC
core   +4 more sources

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

open access: yesAdvanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang   +5 more
wiley   +1 more source

Calcitonin negative Medullary Thyroid Carcinoma: a challenging diagnosis or a medical dilemma?

open access: yesBMC Endocrine Disorders, 2019
Background Medullary thyroid carcinoma is a neuroendocrine tumor belonging form a malignant growth of the thyroid parafollicular C-cells, representing from 1 to 10% of all thyroid cancer.
Claudio Gambardella   +12 more
doaj   +1 more source

Medullary Carcinoma of the Gastrointestinal Tract: Report on Two Cases with Immunohistochemical and Molecular Features

open access: yesDiagnostics, 2021
Medullary carcinoma of the colon is a rare histological variant characterized by a poorly differentiated morphology, an aberrant immunophenotype, and microsatellite instability.
Cristina Colarossi   +7 more
doaj   +1 more source

Medullary Carcinoma of the Thyroid

open access: yesCancer Control, 2000
Medullary thyroid cancer (MTC) is a distinct C-cell tumor of the thyroid. We review the oncogenesis and management of both sporadic tumors and those tumors arising as part of specific inherited syndromes. The RET proto-oncogene plays a role in the development of inherited forms of MTC and has become important in the clinical management of patients and ...
G W, Randolph, D, Maniar
openaire   +2 more sources

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