Results 31 to 40 of about 31,781 (199)

A Diagnostic Dilemma: A Young Boy with Loss of Weight, Pulmonary Infiltrates and Cervical Lymphadenitis [PDF]

Journal of Clinical and Diagnostic Research, 2013
Cervical lymphadenitis is a common finding in young adults in a country like India, where tuberculosis is endemic. We are presenting the case of a young boy who presented with low grade fever, dry cough, weight loss, and a cervical swelling. His chest X-
Asmita A. Mehta, Sunil Kumar K., Rajesh Venkitakrishnan   +2 more
doaj   +1 more source

Calcitonin-secreting neuroendocrine neoplasms of the lung: a systematic review and narrative synthesis

Endocrine Connections, 2021
Calcitonin-secreting neuroendocrine neoplasms of the lung are rare, with few cases reported in the literature. Differentiating between medullary th yroid carcinoma and an ectopic source of calcitonin secretion can represent a complex diagnostic conundrum
David C Llewellyn, Rajaventhan Srirajaskanthan, Royce P Vincent, Catherine Guy, Eftychia E Drakou, Simon J B Aylwin, Ashley B Grossman, John K Ramage, Georgios K Dimitriadis   +8 more
doaj   +1 more source

Medullary Thyroid Carcinoma Without Calcitonin: A Case Linking Ultimobranchial Bodies to Tumor Evolution

Pathophysiology
Medullary thyroid carcinoma (MTC) is a thyroid tumor with neuroendocrine properties purportedly derived from C-cells. The biochemical activity of medullary thyroid carcinoma includes the production of calcitonin and carcinoembryonic antigen, which are ...
Ion Prisneac, Abigail I. Wald, Chelsea Bragg, John A. Ozolek   +3 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Medullary carcinoma of the thyroid

Journal of British Surgery, 1969
A clinical study was conducted using histological slides of all cases diagnosed as carcinoma of the thyroid in the United Birmingham (England) Hospitals since 1940 and in the Regional Histological Collection from 1953-67. A total of 23 patients or 8% were found to have medullary carcinonma.
C R, Williams, D B, Brewer
openaire   +2 more sources

Pediatric Medullary Thyroid Carcinoma [PDF]

Journal of Pediatric Oncology, 2016
Medullary thyroid carcinoma (MTC), which originates from thyroid parafollicular C cells, accounts for 3 to 5% of thyroid malignancies. MTC occurs either sporadically or in an inherited autosomal dominant manner. Hereditary MTC occurs as a familial MTC or as a part of multiple endocrine neoplasia (MEN) type 2A and B syndromes.
Starenki, Dmytro, Park, Jong-In
openaire   +2 more sources

Multiple endocrine neoplasia similar to human subtype 2A in a dog: Medullary thyroid carcinoma, bilateral pheochromocytoma and parathyroid adenoma [PDF]

Open Veterinary Journal, 2016
Human multiple endocrine neoplasia subtype 2A (MEN 2A) is characterized by medullary thyroid carcinoma, pheochromocytoma and parathyroid hyperplasia or adenoma in the same individual.
E.A. Soler Arias, V.A. Castillo, R.H. Trigo, M.E. Caneda Aristarain   +3 more
doaj   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Diarrhea and medullary carcinoma of the thyroid [PDF]

Cancer, 1973
A retrospective analysis of data from all cases of medullary carcinoma of the thyroid seen at the Mayo Clinic from 1927 to 1969 was done to document the incidence and clinical patterns of diarrheal syndromes associated with this condition. 11 patients with histologically confirmed carcinoma of the thyroid were included.
C M, Steinfeld, C G, Moertel, L B, Woolner   +2 more
openaire   +2 more sources

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source