Pediatric thyroid disease: when is surgery necessary, and who should be operating on our children? [PDF]
Surgical diseases of the thyroid in the pediatric population represent a diverse set of both benign and malignant conditions. Overall, incidence is rare.
Breuer, Christopher +3 more
core +1 more source
Hypercalcitoninemia is not pathognomonic of medullary thyroid carcinoma
Hypercalcitoninemia has frequently been reported as a marker for medullary thyroid carcinoma. Currently, calcitonin measurements are mostly useful in the evaluation of tumor size and progression, and as an index of biochemical improvement of medullary ...
Sergio PA Toledo +5 more
doaj +1 more source
Mutational Analysis in Pediatric Thyroid Cancer and Correlations with Age, Ethnicity, and Clinical Presentation. [PDF]
BackgroundWell-differentiated thyroid cancer (WDTC) incidence in pediatrics is rising, most being papillary thyroid carcinoma (PTC). The objective of the study was to assess the prevalence of different mutations in pediatric WDTC and correlate the ...
Cheng, Shih-Min +9 more
core +1 more source
Coexistence of medullary thyroid carcinoma and primary hyperparathyroidism (PHPT) is well described, however, the association of non-medullary thyroid cancer and PHPT is less recognized.
Mehmet Aşık +5 more
doaj +1 more source
Mutations of the ret protooncogene in German multiple endocrine neoplasia families: Relation between genotype and phenotype. [PDF]
It has been suggested that not only the position but also the nature of the mutations of the ret protooncogene strongly correlate with the clinical manifestation of the multiple endocrine neoplasm type 2 (MEN 2) syndrome.
Deckart, H. F. +15 more
core +1 more source
Metachronous Follicular Variant of Papillary Thyroid Microcarcinoma in a Case of Medullary Carcinoma Thyroid [PDF]
Medullary carcinoma and papillary thyroid carcinoma arise from the different cells. Simultaneous occurrence of both types is rare. Medullary carcinomas are characterised by calcitonin positivity.
Neelam Sood, Binit Kumar Khandelia
doaj
Purpose: To explore the clinical value of ultrasound in the diagnosis of medullary thyroid carcinoma by comparing with enhanced computed tomography. Methods: This retrospective study was performed on 62 patients with pathologically confirmed medullary ...
Liang Wang MD +5 more
doaj +1 more source
IGF-I influences everolimus activity in medullary thyroid carcinoma [PDF]
Context: Medullary thyroid carcinoma (MTC) is a rare tumor originating from thyroid parafollicular C cells. It has been previously demonstrated that insulin-like growth factor I (IGF-I) protects MTC from the effects of antiproliferative drugs. Everolimus,
degli Uberti, Ettore C. +9 more
core +1 more source
Calcitonin negative Medullary Thyroid Carcinoma: a challenging diagnosis or a medical dilemma?
Background Medullary thyroid carcinoma is a neuroendocrine tumor belonging form a malignant growth of the thyroid parafollicular C-cells, representing from 1 to 10% of all thyroid cancer.
Claudio Gambardella +12 more
doaj +1 more source
Acoustic radiation force impulse imaging for differentiation of thyroid nodules [PDF]
Background: Acoustic Radiation Force Impulse (ARFI)-imaging is an ultrasound-based elastography method enabling quantitative measurement of tissue stiffness.
Berner, Christian +9 more
core +3 more sources

