Results 31 to 40 of about 2,661,290 (359)

Safety, tolerability, and immunogenicity of a DNA-based vaccine (INO-4700) against Middle East respiratory syndrome coronavirus: phase 2a study in healthy volunteers

Frontiers in Immunology
BackgroundMiddle East respiratory syndrome coronavirus (MERS-CoV) poses an ongoing public health risk with a 36% case-fatality rate and no licensed vaccines.
Joseph T. Agnes, Sarah A. Marcus, Sahem S. Al-Ghraibeh, Suleimman Ahmad Al-Sweedan, Josphat Kosgei, Bernhards Ogutu, ShuPing Yang, Kathleen A. Walker, Bonaventure Orizu, Kate E. Broderick, Jean Boyer, Stephanie Ramos, Matthew P. Morrow, Kimberly Kraynyak, Albert J. Sylvester, Elisabeth Gillespie, David Liebowitz, Laurent M. Humeau   +17 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Bactericidal antibiotics induce programmed metabolic toxicity

Microbial Cell, 2016
The misuse of antibiotics has led to the development and spread of antibiotic resistance in clinically important pathogens. These resistant infections are having a significant impact on treatment outcomes and contribute to approximately 25,000 deaths in ...
Aislinn D. Rowan, Damien J. Cabral, Peter Belenky   +2 more
doaj   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Phyllosphere 2022: 11th International Symposium on Leaf Surface Microbiology

Phytobiomes Journal, 2023
This Meeting Review article offers a synthesis of the science presented and discussed at the recently held 11th International Symposium on Leaf Surface Microbiology, also known as Phyllosphere 2022, at the University of California–Davis (UC Davis), 17 to
Johan H. J. Leveau, Gitta L. Coaker, Maria L. Marco   +2 more
doaj   +1 more source

Banff 2013 Meeting Report: Inclusion of C4d‐Negative Antibody‐Mediated Rejection and Antibody‐Associated Arterial Lesions

American Journal of Transplantation, 2014
The 12th Banff Conference on Allograft Pathology was held in Comandatuba, Brazil, from August 19–23, 2013, and was preceded by a 2‐day Latin American Symposium on Transplant Immunobiology and Immunopathology.
M. Haas, B. Sis, L. Racusen, K. Solez, D. Glotz, R. Colvin, M. Castro, D. S. David, E. David‐Neto, S. Bagnasco, L. Cendales, L. Cornell, A. Demetris, C. Drachenberg, C. Farver, A. Farris, I. Gibson, E. Kraus, H. Liapis, A. Loupy, V. Nickeleit, P. Randhawa, E. Rodriguez, D. Rush, R. Smith, Carmela D. Tan, W. Wallace, M. Mengel   +27 more
semanticscholar   +1 more source

Why emerging leaders should focus on being good postdoctoral supervisors

FEBS Letters, EarlyView.
Swamped with work and suddenly a new student is waiting at your doorstep for supervision? Great—this is your chance! In this article, we share tips on how postdocs can strengthen their leadership skills while supervising students. This image has been created using DALL·E. Many postdocs work as leaders later in their career.
Hannah Rostalski, Clara Oudenaarden, Miao Tian, Diyavarshini Gopaul, Anita Kurilla, Pelin Gülizar Ersan   +5 more
wiley   +1 more source

The Banff 2015 Kidney Meeting Report: Current Challenges in Rejection Classification and Prospects for Adopting Molecular Pathology

American Journal of Transplantation, 2016
The XIII Banff meeting, held in conjunction the Canadian Society of Transplantation in Vancouver, Canada, reviewed the clinical impact of updates of C4d‐negative antibody‐mediated rejection (ABMR) from the 2013 meeting, reports from active Banff Working ...
A. Loupy, M. Haas, K. Solez, L. Racusen, D. Glotz, D. Serón, B. Nankivell, R. Colvin, M. Afrouzian, E. Akalin, N. Alachkar, S. Bagnasco, Jan Becker, L. Cornell, C. Drachenberg, D. Dragun, H. Kort, I. Gibson, E. Kraus, C. Lefaucheur, C. Legendre, H. Liapis, T. Muthukumar, V. Nickeleit, B. Orandi, W. Park, M. Rabant, P. Randhawa, E. Reed, C. Roufosse, S. Seshan, B. Sis, H. K. Singh, C. Schinstock, A. Tambur, A. Zeevi, Michael Mengel   +36 more
semanticscholar   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source