Atypical presentation of acute idiopathic megacolon in a 14-year-old patient
In clinical practice the term “megacolon” is used to indicate a marked dilatation of the cecum and the sigmoid colon (>12 and 6.5 cm, respectively) (1).
B. Barakat +14 more
doaj +1 more source
Toxic megacolon complicating a first course of Crohn’s disease: about two cases
Toxic megacolon is a rare and serious complication of Crohn’s disease. Because of the associated high morbidity and mortality, early recognition and management of toxic megacolon is important.
Rania Hefaiedh +4 more
doaj +1 more source
The Kif26a protein-coding gene has been identified as a negative regulator of the GDNF-Ret signaling pathway in enteric neurons. The aim of this study was to investigate the influence of genetic background on the phenotype of Kif26a-deficient (KO ...
Yukiko Ohara +11 more
doaj +1 more source
Clinical and manometric investigation in constipated Chagasic patients with and without megacolon
Background: Chagasic colopathy is the second most common digestive manifestation, and constipation is the main symptom. The absence of the Rectoanal Inhibitory Reflex plays an important role in constipation and anal manometry is crucial for appropriate ...
Arminda Caetano de Almeida e Leite +5 more
doaj +1 more source
MEGACÓLON TÓXICO POR RETOCOLITE ULCERATIVA
Valesca de Souza Ueoka +6 more
doaj +3 more sources
Caracterização dos canais de k+ voltagem dependentes (kv) no cólon de pacientes chagásicos portadores e não portadores de megacólon [PDF]
Chagas disease remains a serious health problem, especially in the Americas. It is present in 21 countries in the Americas, with about 30,000 new cases per year.
Mendonça, Claudio Ferreira de
core +1 more source
The association between inflammatory processes and intestinal neuronal destruction during the progression of Chagasic megacolon is well established. However, many other components play essential roles, both in the long-term progression and control of the
José Rodrigues do Carmo Neto +9 more
doaj +1 more source
The "GABAergic Brake" on the Spinal Defecation Reflex: A Proposed Neurobiological Model Explaining Clozapine- and Benzodiazepine-Induced Gastrointestinal Hypomotility and Ogilvie's Syndrome. [PDF]
Synergistic “Double Brake” Model on the Spinal Defecation Center in Clozapine‐Induced Constipation. Real‐world data shows BZDRs increase laxative risk in schizophrenia. Mitigating the central GABAergic brake via sedative optimization and maintaining gut microbiota homeostasis prevents fatal Ogilvie's syndrome.
Nagamine T.
europepmc +2 more sources
Ocorrência de dolicocólon sem megacólon em chagásicos crônicos [PDF]
INTRODUÇÃO: Desde 1970, suspeita-se que o alongamento do retossigmoide pode ocorrer como manifestação isolada da colopatia chagásica. MÉTODOS: Para testar esta hipótese, 210 pacientes soropositivos e 63 soronegativos fizeram enema opaco e as radiografias
Hernandez, Esperanza Bernal +3 more
core +1 more source
MEGACÓLON COM FORMAÇÃO DE FECALOMA POR OBSTRUÇÃO EXTRAMURAL EM FELINO
O megacólon é definido como o aumento persistente e crônico do diâmetro colônico associado à constipação. A constipação pode evoluir para o fecaloma, o qual caracteriza-se pelo grande volume e endurecimento das fezes.
Dorneles Trindade, Natasha +1 more
core +1 more source

