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Megaloblastic anaemia: Folic acid and vitamin B12 metabolism
Folic acid and cobalamin are B-group vitamins that play an essential role in many cellular processes. Deficiency in one or both of these vitamins causes megaloblastic anaemia, a disease characterized by the presence of megaloblasts.
H.B. Castellanos-Sinco +6 more
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Surviving Extreme Anaemia [PDF]
Before the development of transfusion medicine, severe anaemia was an important cause of morbidity and mortality. The discovery of haematopoietic mechanisms and essential nutrients made it possible to easily treat and prevent this condition. Nevertheless,
Joana Esteves +5 more
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Malarial anaemia and nitric oxide induced megaloblastic anaemia:a review on the causes of malarial anaemia [PDF]
Direct destruction and ineffective erythropoesis does not adequately explain the cause of anaemia in malaria. It is possible that there are more other mechanisms involved besides the causes described till date in malarial anaemia.
Prasanna Pradhan
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Osteopoikilosis is an uncommon hereditary dysplasia of skeleton characterized by small sclerotic foci clustered mainly in periarticular osseus regions. The radiographic pattern is pathognomonic.
Irena Zimmermann-Górska
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An extremely rare case of Rogers syndrome or thiamine responsive megaloblastic anemia
Rogers syndrome is an extremely rare autosomal recessive syndrome of which only 100 cases are known worldwide. It is characterized by thiamine-responsive megaloblastic anaemia, diabetes mellitus and sensorineural deafness.
Gurpreet Kaur +4 more
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Megaloblastic anaemia in infancy or early childhood and diabetes as leading symptoms of the TRMA syndrome [PDF]
Diabetes mellitus may occur in children and adolescents as an independent disease, most frequently as autoimmune type 1 diabetes, or can coexist with other abnormalities. If diabetes coincides with other disorders occurring sequentially, a syndromic form
Agnieszka Zmysłowska +1 more
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Differential Cell Count of Bone Marrow Aspirates in Steady-state Sickle Cell Anaemia Patients
Summary Background: Megaloblastic arrest of the bone marrow is one of the causes of anaemic crises in patients with sickle cell anaemia. The diagnosis of this condition will require that the reference level of megalobalastosis during steady state be ...
Akinsulie AO , Akanmu AS , Esan OA
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To Evaluate Clinical Spectrum of Megaloblastic Anemia in A Tertiary Care Hospital Central India [PDF]
Background: Megaloblastic anaemia is one of the frequently occurring diseases in a developing country such as India. Megaloblastic anemia occurs mainly because of vitamin B12 and folate deficiency.
Sharma, A. K. (Ashish) +2 more
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AMINOACIDURIA AND MEGALOBLASTIC ANAEMIA [PDF]
Urinary amino-acid chromatograms from 23 patients with megaloblastic anaemia have been studied before and after therapy. The most consistent abnormality was an increased taurine or increased taurine/glycine ratio. This was not related directly to deficiency of vitamin B12 or folic acid or to the degree of anaemia.
D, FOWLER +3 more
openaire +2 more sources
Megaloblastic anaemia, diabetes and deafness in a 2-year old child [PDF]
Megaloblastic anaemia in childhood usually occurs as a result of dietary folate deficiency or, rarely, congenital disorders of vitamin B12 metabolism. We present a 2-year-old girl with megaloblastic anaemia and insulin-dependent diabetes mellitus, both ...
Hartley, Patricia S +3 more
core +1 more source

