Results 171 to 180 of about 157,342 (355)

Pharmacogenetics of follicle‐stimulating hormone action in the male

open access: yesAndrology, EarlyView.
Abstract Male factor infertility (MFI) is involved in half of the cases of couple infertility. The follicle‐stimulating hormone (FSH) therapy is considered efficient to improve semen parameters and pregnancy rate in patients with idiopathic MFI, following the lesson learned from hypogonadotropic hypogonadism.
Andrea Graziani   +7 more
wiley   +1 more source

The role of iron in normal and impaired testicular function

open access: yesAndrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer   +2 more
wiley   +1 more source

Spatial transcriptomics mapping of immune cell and TGFβ signalling pathway heterogeneity in testicular germ cell tumours

open access: yesAndrology, EarlyView.
Abstract Background Testicular germ cell tumours (TGCTs) are amongst the most common malignancies in young men, and their incidence is increasing worldwide. Tissue heterogeneity hampers efforts to understand how TGCT precursors (termed germ cell neoplasia in situ; GCNIS) emerge and progress, restricting elucidation of new strategies for diagnosis and ...
Sarah C. Moody   +6 more
wiley   +1 more source

Gender‐affirming hormone therapy: Effect on semen quality and use of fertility preservation

open access: yesAndrology, EarlyView.
Abstract Fertility preservation (FP) is a fundamental part of gender care. Gender‐affirming hormone therapy (GAHT) involves the use of drugs that could be potential risk factors for fertility. Therefore, FP is recommended before beginning the gender‐affirmation process.
Anna Chiara Conflitti   +7 more
wiley   +1 more source

Effects of neonatal hypothyroidism on testicular development and undifferentiated spermatogonia in prepubertal rats

open access: yesAndrology, EarlyView.
Abstract Background Thyroid hormones play a key role in testicular development, particularly in the regulation of Sertoli cell proliferation and differentiation. While congenital hypothyroidism is common and treatable, the effects of thyroid hormone insufficiency on early testicular development during the neonatal period remain unclear. Objectives This
Daisuke Matsumoto   +10 more
wiley   +1 more source

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