Results 181 to 190 of about 157,342 (355)

A characteristic gene expression profile regulated by ACIN1::NUTM1 fusion in a newly identified infant leukaemic cell line and an ACIN1::NUTM1‐inducible model

open access: yesBritish Journal of Haematology, EarlyView.
An ACIN1::NUTM1‐positive ALL cell line, KOPN32, which was previously established from a relapsed infant‐ALL case, was newly identified. Comparison using 94 BCP‐ALL cell lines, an ACIN1::NUTM1‐inducible ALL model and clinical sample data revealed upregulation of HOXA9, HOXA10, SKIDA1 and BMI1, indicating direct involvement of ACIN1::NUTM1 fusion in the ...
Minori Tamai   +13 more
wiley   +1 more source

Mechanopharmacology of cellular microenvironment stiffness: Therapeutic strategies for age‐related diseases

open access: yesBritish Journal of Pharmacology, EarlyView.
Ageing brings about various biochemical, structural and mechanical alterations within tissues, profoundly impacting cellular behaviour and function. One of the hallmark changes observed with ageing is an increase in cellular microenvironment stiffness, a biomechanical property influenced by intrinsic factors within the cell and extrinsic factors from ...
Wang HaiYang   +3 more
wiley   +1 more source

Reversibility of sex changes in the plant kingdom: more important than we thought?

open access: yesBiological Reviews, EarlyView.
ABSTRACT Compared to animals, plants show a wide range of reproductive strategies with different degrees of sex separation (e.g. dioecy, monoecy, hermaphroditism). While sex expression was previously thought to be genetically determined and fixed in plants, accumulating evidence suggests that sex expression can change reversibly even within one ...
Iris Sammarco   +3 more
wiley   +1 more source

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