Results 41 to 50 of about 149,546 (296)

Spo13 prevents premature cohesin cleavage during meiosis [version 1; peer review: 2 approved, 1 approved with reservations]

open access: yesWellcome Open Research, 2019
Background: Meiosis produces gametes through two successive nuclear divisions, meiosis I and meiosis II. In contrast to mitosis and meiosis II, where sister chromatids are segregated, during meiosis I, homologous chromosomes are segregated. This requires
Stefan Galander   +3 more
doaj   +1 more source

Meiosis: How Male Flies Do Meiosis [PDF]

open access: yesCurrent Biology, 2002
In meiosis in male fruitflies, chromosome pairing events do not facilitate genetic exchange, but rather create bivalents that can be sequestered to discrete pockets of the prophase nucleus. This assignment of homologs to a common pocket likely facilitates the orientation of homologous centromeres to opposite poles.
openaire   +2 more sources

Cell proliferation and differentiation kinetics during spermatogenesis in Hydra carnea [PDF]

open access: yes, 1985
Spermatogenesis inHydra carnea was investigated. The cell proliferation and differentiation kinetics of intermediates in the spermatogenesis pathway were determined, using quantitative determinations of cell abundance, pulse and continuous labelling ...
A Brauer   +17 more
core   +1 more source

Essential and checkpoint functions of budding yeast ATM and ATR during meiotic prophase are facilitated by differential phosphorylation of a meiotic adaptor protein, Hop1 [PDF]

open access: yes, 2015
A hallmark of the conserved ATM/ATR signalling is its ability to mediate a wide range of functions utilizing only a limited number of adaptors and effector kinases.
A Alcasabas   +51 more
core   +11 more sources

Distinct and Overlapping Requirements for Cyclins A, B, and B3 in Drosophila Female Meiosis

open access: yesG3: Genes, Genomes, Genetics, 2016
Meiosis, like mitosis, depends on the activity of the cyclin dependent kinase Cdk1 and its cyclin partners. Here, we examine the specific requirements for the three mitotic cyclins, A, B, and B3 in meiosis of Drosophila melanogaster.
Mohammed Bourouh   +5 more
doaj   +1 more source

Spatial single-cell sequencing of meiosis I arrested oocytes indicates acquisition of maternal transcripts from the soma

open access: yesCell Reports, 2023
Summary: Maternal RNAs are stored from minutes to decades in oocytes throughout meiosis I arrest in a transcriptionally quiescent state. Recent reports, however, propose a role for nascent transcription in arrested oocytes.
Kenneth A. Trimmer   +6 more
doaj   +1 more source

Errors in chromosome segregation during oogenesis and early embryogenesis [PDF]

open access: yes, 2010
Errors in chromosome segregation occurring during human oogenesis and early embryogenesis are very common. Meiotic chromosome development during oogenesis is subdivided into three distinct phases.
A Dyban   +65 more
core   +1 more source

Chromosome architecture and low cohesion bias acrocentric chromosomes towards aneuploidy during mammalian meiosis

open access: yesNature Communications
Aneuploidy in eggs is a leading cause of miscarriages or viable developmental syndromes. Aneuploidy rates differ between individual chromosomes. For instance, chromosome 21 frequently missegregates, resulting in Down Syndrome.
Eirini Bellou   +8 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Black Hole Meiosis

open access: yes, 2010
The enumeration of BPS bound states in string theory needs refinement. Studying partition functions of particles made from D-branes wrapped on algebraic Calabi-Yau 3-folds, and classifying states using split attractor flow trees, we extend the method for
A Collinucci   +20 more
core   +1 more source

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