Results 181 to 190 of about 5,667,091 (281)

Extending the Use of Mendelian Randomisation With Non‐Inherited Variants to Assess Socially Transmitted Parental Exposures Under Assortative Mating

Genetic Epidemiology, Volume 50, Issue 1, February 2026.
ABSTRACT A longstanding aim of developmental psychology and epidemiology is to understand the causal effects of parental phenotypes on offspring outcomes. Traditional approaches often fail to account for confounding and reverse causation. We evaluate the use of Mendelian randomisation with non‐inherited variants (MR‐NIV) to address these limitations ...
Benjamin Woolf, Amy Mason, Chin Yang Shapland, Hyunseung Kang, Hannah M. Sallis, Stephen Burgess, Marcus R. Munafò   +6 more
wiley   +1 more source

Genetic and epigenetic insights into non-obstructive azoospermia: mechanisms, biomarkers, and clinical perspectives. [PDF]

Reprod Biol Endocrinol
Wang X, Nie L, Hong Z, Li L, Fan Q, Ma B, Li Z, Gao Y, Zhang M, Zhang Y, Wang M.   +10 more
europepmc   +1 more source

Testicular Morphology and Spermatogenesis in Potamotrygon motoro: Insights Into Reproduction of Freshwater Stingrays

Journal of Morphology, Volume 287, Issue 2, February 2026.
Electron microscopy of Potamotrygon motoro spermatozoa. a – Illustration of a schematic sperm cell depicting the helical head, intermediate piece (midpiece), and flagellum. b ‐ Helical heads (Hh) of spermatozoa inserted into the cytoplasm of Sertoli cells (S) through openings in the plasma membrane. Scales: 10 μm.
Maria Luiza Ribeiro Delgado, Patricia Postingel Quirino, Luciane Gomes‐Silva, Viktoriya Dzyuba, Borys Dzyuba, Alexandre Ninhaus‐Silveira, Rosicleire Veríssimo‐Silveira   +6 more
wiley   +1 more source

A male-transmitted B chromosome undergoes strong meiotic drag in females of the jewel wasp Nasonia vitripennis. [PDF]

PLoS Biol
Ferree PM, Cummings J, Garman E, Solomon J, Martinez KS.   +4 more
europepmc   +1 more source

Identification of a Novel Missense Homozygous Variant in LINS1 in Two Distinct Iranian Families With Consanguineous Marriage

Molecular Genetics &Genomic Medicine, Volume 14, Issue 2, February 2026.
A novel homozygous missense variant in LINS1 (c.1354G>C; p.Ala452Pro) was identified in two consanguineous families with autosomal recessive intellectual disability, supporting the gene's role in neurodevelopment and its relevance in genetic diagnosis and counseling of ARID. Reported pathogenic LINS1 variants.
Elham Alimoradi, Parham Nejati, Arash Salmaninejad, Nafiseh Falsafi, Fatemeh Molavi, Mohamad Javad Alibakhshi, Filippo Pinto e Vairo, Eric W. Klee, Reza Alibakhshi   +8 more
wiley   +1 more source

Human selection maintains karyotype integrity of highly unstable genomic cultivated autotetraploid potato (<i>Solanum tuberosum</i>). [PDF]

Sci Adv
Yang L, Bai Y, Chao G, Zhao K, Xu J, Sun M, Zhang H, Niu Y, Li K, Xiong Z, Cao Y, Wang F, Hai B, Cao C, Yin Y, Lin T, Wang Y, Gong X, Wu L, Jiang J, Xiong Z.   +20 more
europepmc   +1 more source

Friends or foes? Polyploidy and competition in a grassland geophyte

Oikos, Volume 2026, Issue 2, February 2026.
Previous studies have suggested polyploids may possess a competitive advantage over diploids, due to their larger size, increased vigour or ability to better respond to abiotic stress. However, few studies have tested the effect of polyploidy on competitive ability directly, and only relatively recently has this oversight begun to be addressed. Here we
Damian Vaz de Sousa, Michelle Greve, Nicolette J. Taylor, Kenneth C. Oberlander   +3 more
wiley   +1 more source

Decreased PTGES2 Farnesylation in Granulosa Cells Compromises PGE2‐Dependent Cumulus Expansion and Oocyte Maturation During Ovarian Aging

Aging Cell, Volume 25, Issue 2, February 2026.
A schematic showing decreased PTGES2 farnesylation in granulosa cells compromises PGE2‐dependent cumulus expansion and oocyte maturation during ovarian aging. In young ovaries, PTGES2 farnesylation of GCs regulates the process of cumulus expansion and oocyte maturation by facilitating PGE2 production.
Sainan Zhang, Jiahui Qi, Chuanming Liu, Huidan Zhang, Bichun Guo, Die Wu, Yicen Liu, Xin Zhen, Yang Zhang, Nannan Kang, Jidong Zhou, Guijun Yan, Chaojun Li, Lijun Ding, Haixiang Sun   +14 more
wiley   +1 more source

Crosstalk between cohesins and axis proteins determines meiotic chromosome architecture in Sordaria macrospora. [PDF]

PLoS Genet
Yefsah K, Habbi M, Budin K, Bourbon HM, Zickler D, Espagne E, Boisnard S.   +6 more
europepmc   +1 more source

Mechanopharmacology of cellular microenvironment stiffness: Therapeutic strategies for age‐related diseases

British Journal of Pharmacology, Volume 183, Issue 4, Page 945-956, February 2026.
Ageing brings about various biochemical, structural and mechanical alterations within tissues, profoundly impacting cellular behaviour and function. One of the hallmark changes observed with ageing is an increase in cellular microenvironment stiffness, a biomechanical property influenced by intrinsic factors within the cell and extrinsic factors from ...
Wang HaiYang, Cheong Dorothy Hui Juan, Lee Zhao‐Yong, Tran Thai   +3 more
wiley   +1 more source