Loss of E3 ligase HvST1 function substantially increases distal crossover frequency
Summary This study characterizes the function of a grass‐specific E3 ubiquitin ligase, HvST1, in regulating synapsis and crossover (CO) formation during meiosis in barley (Hordeum vulgare). In large‐genome cereals, COs are predominantly restricted to distal chromosomal regions, limiting genetic recombination and breeding flexibility.
Jamie Neil Orr +8 more
wiley +1 more source
Meiotic Recombination May Be Initiated by Copy Choice During DNA Synthesis Rather than Break/Join Mechanism. [PDF]
Jia L, Yin N, Wang X, Li J, Li L.
europepmc +1 more source
Contemporary hybridization among Arabis floodplain species creates opportunities for adaptation
Summary Hybridization between closely related species is increasingly recognized as a major source of biodiversity. Yet, whether it can create advantageous trait combinations while purging harmful alleles remains unknown. To address this question, we studied Arabis nemorensis and Arabis sagittata, two endangered species that currently hybridize in a ...
Neda Rahnamae +13 more
wiley +1 more source
Early female germline development in <i>Xenopus laevis</i>: Stem cells, nurse cells, and germline cysts. [PDF]
Davidian A, Spradling AC.
europepmc +1 more source
hnRNPU Safeguards Oocyte Development and Female Fertility via Regulation of Alternative Splicing
Heterogeneous nuclear ribonucleoprotein U (hnRNPU) is essential for oocyte development and female fertility. Oocyte‐specific deletion of Hnrnpu leads to follicular arrest, impaired meiotic maturation, mitochondrial dysfunction, and infertility.
Jinmei Li +8 more
wiley +1 more source
Loss of full-length DAZL isoform disrupts PABPC1-dependent translational regulation and meiosis. [PDF]
Li X +9 more
europepmc +1 more source
This study integrates bulk and single‐cell RNA‐seq data to reveal significant B cell receptor (BCR) repertoire expansion, especially IgG isotype amplification, in T cell‐mediated rejection (TCMR) after kidney transplantation. Multi‐omic integration identifies plasma cells as the main BCR carriers in graft tissue and MEI1 as a key regulator promoting ...
He Zhang +5 more
wiley +1 more source
Beyond recombination: Exploring the impact of meiotic frequency on genome-wide genetic diversity. [PDF]
Ollivier L, Charlesworth B, Pouyet F.
europepmc +1 more source
The nuclear transport factor IPO5 revealed as a critical mediator of male germline development†. [PDF]
Young JC +10 more
europepmc +1 more source
Single cell RNA-sequencing reveals no evidence for meiotic sex chromosome inactivation in the threespine stickleback fish. [PDF]
Shaw DE, Ross WD, Lambert AV, White MA.
europepmc +1 more source

