Results 171 to 180 of about 127,807 (252)

Community Head and Neck Cancer Knowledge, Engagement, Research, and Screening (CHECKERS): Protocol for a Community‐Engaged Approach to Head and Neck Cancer Prevention

open access: yesCancer Nexus, EarlyView.
ABSTRACT Introduction Unequal access to care is associated with disparities in prevention, early detection, and outcomes of head and neck cancer (HNC), especially in underserved populations. Community‐engaged research (CEnR) aims to build capacity for community members to address health inequity via bidirectional partnerships with healthcare ...
Nicholas A. Frisco   +11 more
wiley   +1 more source

Population Pharmacokinetics and Exposure‐Response Analyses to Support Cofetuzumab Pelidotin (ABBV‐647) Dose Optimization in Non‐Small Cell Lung Cancer Patients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Cofetuzumab pelidotin (Cofe‐P) is an anti‐protein tyrosine kinase 7 (PTK7) antibody‐drug conjugate (ADC) being investigated for the treatment of adults with PTK7‐expressing, recurrent non‐small cell lung cancer (NSCLC). The first‐in‐human (FIH) trial demonstrated tolerability of dosages ≤ 2.8 mg/kg once every 3 weeks (Q3W) and ≤ 3.2 mg/kg Q2W ...
Carla Biesdorf   +8 more
wiley   +1 more source

Model‐based clinical pharmacology profiling of subcutaneous nivolumab in renal cell carcinoma: Bridging to alternative dosing regimens and indications

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
A novel model‐informed drug development (MIDD) approach was employed to derive the coprimary endpoints (time‐averaged serum concentration over 28 days [Cavgd28] and minimum serum concentration at steady state [Cminss]) of the phase III CheckMate 67T study (NCT04810078).
Yue Zhao   +5 more
wiley   +1 more source

The Synergistic Impact of Corporate Social Responsibility and Environmental, Social, and Governance Disclosure on Green Innovation: Practical Implications for Sustainability‐Oriented Innovation Strategies

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This research examines the synergistic influence of corporate social responsibility (CSR) and environmental, social, and governance (ESG) disclosure on green innovation (GI) within Romanian small and medium‐sized industrial enterprises. In light of growing regulatory requirements and the transformation toward a sustainable economy, the study ...
Melinda Timea Fülöp   +1 more
wiley   +1 more source

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