Results 191 to 200 of about 127,807 (252)

Engineering Hierarchical Cellulose Aerogel Networks Toward Decoupled Heat Transfer and Enhanced Multi-Phase Fire Safety. [PDF]

Materials (Basel)
Chen L, Wang H, Ding W, Qian X, Shi C, Pan YT, Wan M, Jing J, Hou Y.   +8 more
europepmc   +1 more source

Preoperative limbic cortical thinning in mesial temporal lobe epilepsy surgical candidates is associated with pre‐existing and de novo postoperative depression

Epileptic Disorders, EarlyView.
Abstract Objective Depression is common in mesial temporal lobe epilepsy (mTLE), but its neuroanatomical basis—and overlap with major depressive disorder (MDD)—remains poorly defined. We investigated whether the cortical and subcortical alterations reported in MDD are also present in mTLE and leveraged the frequent occurrence of depression after ...
Philip Fink‐Jensen, Brice Ozenne, Ane Kloster, Bo Jespersen, Kirsten Vinter, Guido Rubboli, Martin Balslev Jørgensen, Sandor Beniczky, Melanie Ganz, Lars Hageman Pinborg   +9 more
wiley   +1 more source

ForNet: classification of critical forest acoustic events using discriminative CNN representations and ensemble learning. [PDF]

Sci Rep
Krishnamoorthy D, Sai VS, Vishal R, Benezeth Y.   +3 more
europepmc   +1 more source

Prolonged fenfluramine use in open‐label studies of Dravet or Lennox–Gastaut syndromes: Long‐term safety, tolerability, patient global functioning, and considerations for interpreting effectiveness

Epilepsia, EarlyView.
This graphical abstract provides an overview of the content from this open‐label extension study of fenfluramine use in patients with Dravet syndrome or Lennox‐Gastaut syndrome. Abstract Objective Long‐term safety and global functioning are reported in patients with Dravet syndrome (DS) or Lennox–Gastaut syndrome (LGS) treated with fenfluramine in an ...
Antonio Gil‐Nagel, Kelly G. Knupp, Boudewijn Gunning, Domenica Immacolata Battaglia, Elizabeth A. Thiele, Ingrid E. Scheffer, An‐Sofie Schoonjans, Rima Nabbout, Nathalie Villeneuve, Kerstin Alexandra Klotz, Nicola Specchio, Rocio Sanchez‐Carpintero, Marta Zolnowska, Anne‐Liv Schulz, Lily Perrin, Najla Dickson, Mélanie Langlois, Amélie Lothe, Joseph Sullivan   +18 more
wiley   +1 more source

TRPV1-mediated calcium signaling underlies the synergistic pro-apoptotic effects of lidocaine and melatonin in SH-SY5Y neuroblastoma cells. [PDF]

Front Oncol
Aladag E, Ovey IS.
europepmc   +1 more source

Changes in effectiveness and safety in patients with Lennox–Gastaut syndrome transitioning from the fenfluramine randomized controlled trial to open‐label extension study

Epilepsia Open, EarlyView.
This graphical abstract provides an overview of the content from this post hoc analysis describing the trajectories of fenfluramine effectiveness and safety, along with dose changes over time, in patients with Lennox‐Gastaut syndrome. Abstract In the phase 3 randomized controlled trial (RCT; NCT03355209) of fenfluramine in Lennox–Gastaut syndrome (LGS),
Rima Nabbout, Orrin Devinsky, Lieven Lagae, Ingrid E. Scheffer, Renzo Guerrini, Joseph Sullivan, Antonio Gil‐Nagel, Sameer M. Zuberi, Kate Riney, Patrick Healy, Jayne Abraham, Rebecca Zhang Roper, Mélanie Langlois, Amélie Lothe, Kelly G. Knupp   +14 more
wiley   +1 more source

V-SYNTHES2-the next generation tool for structure-based virtual screening of giga-scale chemical spaces. [PDF]

NPJ Drug Discov
Nazarova AL, Sadybekov AV, Sadybekov AA, Protopopov M, Radchenko DS, Moroz YS, Tarkhanova OO, Katritch V.   +7 more
europepmc   +1 more source

Melatonin Improves Cognitive Function and Suppresses Excessive Mitophagy in Rats With Vascular Dementia. [PDF]

CNS Neurosci Ther
Hou SJ, Guo XY, Wang ZG, Chen TY, Li Y, Xu SY.   +5 more
europepmc   +1 more source

Efficacy and safety of fenfluramine in Dravet syndrome: The impact of patient clinical characteristics

Epilepsia Open, EarlyView.
This graphical abstract provides an overview of the content from this post hoc analysis evaluating the efficacy and safety of fenfluramine in patients with Dravet syndrome stratified by age, number of previously attempted antiseizure medications, and SCN1A pathogenic variant status using data pooled from the three pivotal randomized controlled trials ...
Rima Nabbout, Joseph Sullivan, Stéphane Auvin, J. Helen Cross, Orrin Devinsky, Antonio Gil‐Nagel, Renzo Guerrini, Kelly G. Knupp, M. Scott Perry, Rocío Sánchez‐Carpintero, An‐Sofie Schoonjans, Ingrid E. Scheffer, Nicola Specchio, Adam Strzelczyk, James Wheless, Elaine C. Wirrell, Diego Morita, Patrick Healy, Mélanie Langlois, Amélie Lothe, Lieven Lagae   +20 more
wiley   +1 more source

Integrated isothermal shift assay and multi-omics identify melittin as a novel EGFR-targeting peptide to suppress NSCLC. [PDF]

J Transl Med
Zhong C, Gong J, Wei L, Xie RF, Shi P, Yao H, Huang J.   +6 more
europepmc   +1 more source