Results 61 to 70 of about 611,928 (302)
Matrix Viscoelasticity Regulates Dendritic Cell Migration and Immune Priming
Advanced Materials, EarlyView.Matrix viscoelasticity is a key mechanical feature of the tumor microenvironment but remains poorly understood in immune regulation. Here, we develop a tunable collagen platform to decouple viscoelasticity from stiffness and show that slow‐relaxing matrices constrain dendritic cell migration by limiting actomyosin‐driven matrix remodeling, thereby ...
Wei‐Hung Jung +6 more
wiley +1 more source
Diversity in the Irish workplace - lesbian women's experience as nurses [PDF]
, 2010 Work is an area which represents an important part of people’s lives where they encounter the Other. It provides an individual with a sense of who they are in society, through their membership of communities.
Duffy, Mel
core +1 more source
Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors
Advanced Science, EarlyView.Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen +4 more
wiley +1 more source
Multicollinearity and maximum entropy leuven estimator [PDF]
Multicollinearity is a serious problem in applied regression analysis. Q. Paris (2001) introduced the MEL estimator to resolve the multicollinearity problem.
Sougata Poddar
core
Advanced Science, EarlyView.This study reveals that m6A regulators cooperatively upregulate BGN in melanoma, promoting malignancy. Within the tumor microenvironment, CAFs show highest BGN expression. The BGN/MDK axis mediates cancer‐stroma crosstalk, driving normal fibroblast (NF) activation and enhancing the pro‐tumor effect of CAFs, highlighting a promising therapeutic target ...
Hao‐ze Shi +16 more
wiley +1 more source
Frontiers in Public Health, 2017 This paper describes a community coalition–university partnership to address health needs in an underserved US–Mexico border, community. For approximately 15 years, this coalition engaged in community-based participatory research with community ...
Cecilia Ballesteros Rosales +6 more
doaj +1 more source
Photon‐Sphere Modes in Curved Optical Microcavities: A Black‐Hole Analogue Laser
Advanced Science, EarlyView.An optical analogue of a Schwarzschild black hole is realized using curved microcavities that preserve light‐like geodesics. A new family of laser modes confined around the photon sphere is identified alongside conventional whispering‐gallery modes. Analytical theory, numerical simulations, and experiments reveal curvature‐induced confinement, enabling
Chenni Xu +9 more
wiley +1 more source
BMJ OpenBackground There are currently over 38 million individuals around the globe living with the HIV and AIDS. As many HIV prevention and care services emerging for public use services become available to a wider audience, there is a growing need for more ...
Purnima Madhivanan +4 more
doaj +1 more source
Frontiers in Public Health, 2017 BackgroundCompared to the general United States (U.S.) population, Arizona counties along the U.S.–Mexico border have a higher prevalence of dental caries, which can be reduced with adequate fluoride exposure. Because of concern regarding local tap water
Paloma I. Beamer +6 more
doaj +1 more source