Results 41 to 50 of about 127,807 (252)

Least absolute shrinkage and selection operator type methods for the identification of serum biomarkers of overweight and obesity: simulation and application

BMC Medical Research Methodology, 2016
Background The study of circulating biomarkers and their association with disease outcomes has become progressively complex due to advances in the measurement of these biomarkers through multiplex technologies.
Monica M. Vasquez, Chengcheng Hu, Denise J. Roe, Zhao Chen, Marilyn Halonen, Stefano Guerra   +5 more
doaj   +1 more source

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini, Valerio Licursi, Gianmarco Dalla Zanna, Flavio Dal Canto, Melissa Barghigiani, Nunzio Setola, Salvatore Rossi, Antonio Funcis, Filippo M. Santorelli, Gabriella Silvestri, Carlo Casali, Francesca Sardina, Cinzia Rinaldo   +12 more
wiley   +1 more source

Characterization and treatment of leachate of the great agadir discharge by infiltration–percolation onto titaniferous sand

Scientific African, 2019
Our study consists of treating the liquid discharge of the Great Agadir effluents by the infiltration–percolation technique using titaniferous sand (TFS) coming from the Agadir region.
Youssef Azougarh, Mohamed Abbaz, Naima Hafid, Mohmed Benafqir, Mohamed Ez-zahery, Noureddin El Alem   +5 more
doaj   +1 more source

Discordance Between Patient and Physician Global Assessments in Early Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective This study aims to identify factors associated with patient global assessment (PtGA) and physician global assessment (PhGA) and discordance between them in systemic sclerosis (SSc). Methods Data from adults with early SSc (<5 years) from the Collaborative National Quality and Efficacy Registry were included.
Ellen Romich, Alexis Ogdie, Alisa Stephens Shields, Peter A. Merkel, Shervin Assassi, Elana J. Bernstein, Andreea Bujor, Flavia V. Castelino, Lorinda Chung, Luke B. Evnin, Tracy M. Frech, Jessica K. Gordon, Melissa Griffith, Faye N. Hant, Monica L. Harding, Laura K. Hummers, Dinesh Khanna, Kimberly S. Lakin, Dorota J. Lebiedz‐Odrobina, Yiming Luo, Ashima Makol, Maureen D. Mayes, Zsuzsanna H. McMahan, Jerry Molitor, Duncan F. Moore, Julie Paik, Carrie Richardson, Brian Skaug, Ami A. Shah, Ankoor Shah, Virginia Steen, John M. VanBuren, Elizabeth R. Volkmann, Carleigh Zahn, Nora Sandorfi, for the CONQUER Investigators   +35 more
wiley   +1 more source

Reaching Across the Divide: Integrating Equitable Community-Based Qualitative Methods and Trusted Engagement Strategies Into Arizona’s Statewide Maternal and Child Community Assessment

Journal of Primary Care & Community Health
Maternal mortality in the U.S. remains a pressing public health issue, with African American and Indigenous populations experiencing significantly higher rates. In Arizona, maternal mortality reached 30.0 deaths per 100,000 births in 2023, well above the
Martha Moore-Monroy, Sheila Soto, Kizil A. Yusoof, Michelle Perez-Coronado, Tania Felix, Rodrigo Valenzuela Cordova, Kathryn Margaret Tucker Ortiz y Pino, Kelly N. B. Palmer, Martin Celaya, John E. Ehiri   +9 more
doaj   +1 more source

Longitudinal assessment of daily activity patterns on weight change after involuntary job loss: the ADAPT study protocol

BMC Public Health, 2017
Background The World Health Organization has identified obesity as one of the most visible and neglected public health problems worldwide. Meta-analytic studies suggest that insufficient sleep increases the risk of developing obesity and related serious ...
Patricia L. Haynes, Graciela E. Silva, George W. Howe, Cynthia A. Thomson, Emily A. Butler, Stuart F. Quan, Duane Sherrill, Molly Scanlon, Darlynn M. Rojo-Wissar, Devan N. Gengler, David A. Glickenstein   +10 more
doaj   +1 more source

Attitudes Toward Gender-Neutral Spanish: Acceptability and Adoptability

Frontiers in Sociology, 2021
This article presents the results of a survey conducted in January 2020 about attitudes toward gender-neutral language in Argentina. The survey was delivered mainly through social networks to 4,205 participants, and its results help understand the ...
Juan Eduardo Bonnin, Alejandro Anibal Coronel   +1 more
doaj   +1 more source

Engagement Patterns With an Artificial Intelligence Health Coach for Systemic Sclerosis Self‐Management: A Mixed Methods Study

Arthritis Care &Research, EarlyView.
Objective To evaluate utility of an artificial intelligence (AI) health coach for systemic sclerosis (SSc) self‐management and identify patterns associated with participant engagement. Methods We conducted a mixed methods study in which an AI health coach, powered by a large language model (LLM), was used to support self‐management for SSc.
Nirali Shah, Melanie Morris, Cristina Daraban, Sophia Johnson, Susan L. Murphy   +4 more
wiley   +1 more source

MEL-28 N-terminal domains are required for NPC and kinetochore localization.

, 2016
(A) Still images from time-lapse recording of embryo carrying a GFP insertion into the endogenous mel-28 locus. Time is indicated relative to anaphase onset (min:sec).
Georgina Gómez-Saldivar (3164445), Michael Mauro (3164451), Fabio Piano (45589), Allison Lai (3164463), Cristina Ayuso (3164448), Yasushi Hiraoka (52047), Tokuko Haraguchi (342841), Peter Askjaer (3164460), Anita Fernandez (3164457), Yasuhiro Hirano (3164454)   +9 more
core   +1 more source

Mental health and diabetes self-management: assessing stakeholder perspectives from health centers in Northern Mexico

BMC Health Services Research, 2021
Background People living with diabetes have an increased risk of developing mental health issues. Mexico has observed a high prevalence of people living with diabetes suffering from mental health issues, such as anxiety and depression.
Benjamín Aceves, Manuel Ruiz, Maia Ingram, Catalina Denman, David O. Garcia, Purnima Madhivanan, Cecilia Rosales   +6 more
doaj   +1 more source