Results 31 to 40 of about 127,807 (252)

MEL-28 is essential for female meiosis.

, 2016
(A) GFP::MEL-28 (green in merged images) was expressed in oocytes and accumulated at kinetochores of meiotic chromosomes (visualized with mCherry::HisH2B; magenta in merge).
Georgina Gómez-Saldivar (3164445), Michael Mauro (3164451), Fabio Piano (45589), Allison Lai (3164463), Cristina Ayuso (3164448), Yasushi Hiraoka (52047), Tokuko Haraguchi (342841), Peter Askjaer (3164460), Anita Fernandez (3164457), Yasuhiro Hirano (3164454)   +9 more
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Estudo do comportamento reológico do mel Apis mellifera da região de Rio do Oeste/SC [PDF]

, 2006
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Alimentos.O objetivo deste trabalho foi avaliar o comportamento reológico a partir da coleta do mel de abelha Apis mellifera ...
Padilha, Antonio César
core  

Are prevention of mother-to-child HIV transmission service providers acquainted with national guideline recommendations? A cross-sectional study of primary health care centers in Lagos, Nigeria

BMC Health Services Research, 2022
Background Implementation of interventions for the prevention of mother-to-child transmission (PMTCT) of HIV in low- and middle-income countries, faces several barriers including health systems challenges such as health providers’ knowledge and use of ...
B. Okusanya, C. Nweke, L. B. Gerald, S. Pettygrove, D. Taren, J. Ehiri   +5 more
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Characterizing full-shift worker exposures to VOCs in small-sized auto repair shops in the Tucson, Arizona, USA metropolitan area

Scientific Reports
Auto repair shops employ 1% of the US labor force. These workers are constantly exposed to volatile organic compounds (VOCs), which have known and often irreversible health effects, yet exposure studies are sparse.
Nathan Lothrop, Shannon Gutenkunst, Jocelyn Fimbres, Carolina Quijada, Marvin Chaires, Imelda Cortez, Flor Sandoval, Fernanda J. Camargo, Denise Moreno Ramírez, Emma V. Gallardo, Elmira Torabzadeh, Rietta Wagoner, Nicolas Lopez-Galvez, Maia Ingram, Scott Carvajal, Dean Billheimer, Ann Marie Wolf, Paloma I. Beamer   +17 more
doaj   +1 more source

Healthcare system indicators associated with modern contraceptive use in Ghana, Kenya, and Nigeria: evidence from the Performance Monitoring and Accountability 2020 data

Reproductive Health, 2019
Background Public health literature is replete with evidence on individual and interpersonal indicators of modern contraceptive use. There is, however, limited knowledge regarding healthcare system indicators of modern contraceptive use.
Ibitola Asaolu, Velia Leybas Nuño, Kacey Ernst, Douglas Taren, John Ehiri   +4 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Risk factors associated with under-five stunting, wasting, and underweight in four provinces of the Democratic Republic of Congo: analysis of the ASSP project baseline data

BMC Public Health, 2022
Background Determining the magnitude and risk factors of undernutrition in a country that has one of the highest prevalence of undernutrition in the world is paramount for developing contextual interventions.
Joy Kinko Luzingu, Nancy Stroupe, Halimatou Alaofe, Elizabeth Jacobs, Kacey Ernst   +4 more
doaj   +1 more source

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky, Melissa Lopez, Janet Miller, Millenia Jimenez, Eric M. Liotta, Igor J. Koralnik   +5 more
wiley   +1 more source