Results 21 to 30 of about 101,974 (263)
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Análise da competitividade do setor de mel: uma aplicação de caso da Nutrisempre – Itajaí/SC [PDF]
, 2009 TCC (graduação) - Universidade Federal de Santa Catarina. Centro Sócio-Econômico. Economia.O presente estudo tem como objetivo analisar o comportamento da apicultura sob a ótica da competitividade.
Hatada, Talita Leite
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Episode 37: Senator Mel Martinez - An Operación Pedro Pan Survivor [PDF]
, 2023 In Part 3 of “Operación Pedro Pan: The Voices and Stories of Cuba’s Child Exodus—A Knights HistoryCast Mini-Series,” the Department of History’s Sebastian Garcia talked with former U.S. Senator Mel Martinez, who served in the U.S.
Garcia, Sebastian
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MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
, 1940 Photo shows a skier (possibly Mel Fletcher) using a snow-covered house as a ski jumping ...
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Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Estudo do comportamento reológico do mel Apis mellifera da região de Rio do Oeste/SC [PDF]
, 2006 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Alimentos.O objetivo deste trabalho foi avaliar o comportamento reológico a partir da coleta do mel de abelha Apis mellifera ...
Padilha, Antonio César
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Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
FEBS Open Bio, EarlyView.Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
mit vielen schönen Gebättern ausgefertiget und vermehret von Doct. Conrad Mel, Jnspector zu Herssfeld, (nebt des Authoris Portrait und Titel-Kupfer)Frontispiz von Johann Georg ...
Mel, Conrad
core +1 more source