Results 141 to 150 of about 80,543 (306)

Beyond the Classics: The Synergy of AI and Genomics Reveals an Expanded Repertoire of Pigmentation Genes

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Classical approaches for coloration analysis are limited by human low‐resolution phenotyping and genetic analysis. Artificial intelligence allows us to find genes beyond the tip of the iceberg that explain color and pattern diversity in nature. ABSTRACT Pigmentation has long served as a powerful system for exploring gene–trait relationships, yet much ...
Ehsan Pashay Ahi, Nidal Karagic
wiley   +1 more source

An investigation into the role of autoimmunity in vitiligo [PDF]

open access: yes, 2002
Vitiligo is an acquired depigmenting disorder characterised by the loss of functional melanocytes from the cutaneous epidermis. A role for autoimmunity is supported by the presence of circulating antibodies and T lymphocytes which react against ...
Waterman, Elizabeth Ann
core  

Deep learning‐assisted design of nanozyme for immune regulation

open access: yesJournal of Intelligent Medicine, EarlyView.
Overview of nanozyme‐based strategies for inflammatory bowel disease therapy, featuring metal‐based and non‐metallic nanozymes classified by structure, alongside multifunctional and engineered probiotic‐based nanozymes classified by function. Abstract Inflammatory bowel disease (IBD), with rising global incidence and disease burden, is a multifactorial
Ke Chen   +3 more
wiley   +1 more source

The effects of royal jelly on human health: A narrative review of clinical studies

open access: yesJSFA reports, EarlyView.
Abstract Royal jelly (RJ) is a natural bioactive substance with documented effects on human health. This narrative review synthesizes evidence from clinical and clinically relevant experimental studies evaluating the therapeutic potential of RJ.
Georgios Goras   +2 more
wiley   +1 more source

Genetic, structural, and functional characterization of allomelanin from black yeast Exophiala viscosa, a chassis for fungal melanin production

open access: yesApplied Microbiology and Biotechnology
Melanized fungi are known for their remarkable resilience to environmental stress, largely attributed to the protective properties of melanin. In this study, we establish the black yeast Exophiala viscosa as a non-pathogenic, genetically tractable model ...
Tiffany M. Hennessa   +8 more
doaj   +1 more source

Unleashing the power of visible‐near infrared spectroscopy: predicting Golden Delicious apple enzyme activity

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Enzymatic browning is a significant reaction in fruits that affects their color, appearance, and quality. The quality of apples, as a perishable product, is mainly influenced by the activity of two browning‐related enzymes, polyphenol oxidase (PPO) and peroxidase (POD), during storage.
Tarahom Mesri Gundoshmian   +5 more
wiley   +1 more source

Effect of Nanoparticle Distribution on Photothermal Absorption in Binary Mixtures of Colloidal Supraballs

open access: yesAdvanced Photonics Research
Melanin is ubiquitous in nature, and how the arrangement and concentration of melanin affect its optical and thermal properties aids in understanding the role of melanin in natural systems and technological applications.
Hanieh Mohsenzadeh Hedeshi   +6 more
doaj   +1 more source

Cutaneous Pigmentary Changes During Setmelanotide Therapy: Dermoscopic and Confocal Findings in Two Patients

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Setmelanotide is a melanocortin‐4 receptor agonist approved for the treatment of rare forms of genetic obesity. Through off‐target activation of the melanocortin‐1 receptor, it may induce cutaneous pigmentation changes; however, data regarding its effects on melanocytic nevi remain limited.
Martina Cavicchi   +5 more
wiley   +1 more source

Beyond Skin and Eyes: The Medical and Social Burden of Oculocutaneous Albinism in Africa: A Narrative Review

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Oculocutaneous albinism (OCA) is a genetic disorder found worldwide, but its impact is particularly pronounced in the African continent. This results from both a higher prevalence and the persistent myths and superstitions surrounding the condition in many African communities.
Rebecca Donadoni   +3 more
wiley   +1 more source

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