Non-contact, in-vivo, functional, and structural ophthalmic imaging using multimodal photoacoustic remote sensing (PARS) microscopy and optical coherence tomography (OCT) [PDF]
Early diagnosis of ocular diseases improves the understanding of pathophysiology and helps with accurate monitoring and effective treatment. Advanced multimodal ocular imaging platforms play a crucial role in the visualization of the ocular components and provide clinicians with a valuable tool for evaluating different eye diseases. Here, for the first
arxiv
Chemistry of Melanin. IV. Electron Micrography of Natural Melanins.
Summary1. Melanin granules were obtained by differential centrifugation from the S-91 and Harding-Passey transplantable mouse melanomas, from the choroid, ciliary body and iris of the beef eye, and...
Albert J. Dalton+3 more
openaire +3 more sources
Mass spectrometry in ocular drug research
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo+6 more
wiley +1 more source
Mandible composition and properties in two selected praying mantises (Insecta, Mantodea)
Abstract Insects process their food with their cuticle‐based mouthparts. These feeding structures reflect their diversity and can, in some cases, showcase adaptations in material composition, mechanical properties, and shape to suit their specific dietary preferences.
Malo Roze+3 more
wiley +1 more source
Preparation and characterization of natural melanin and its nanocomposite formed by copper doping
Melanin was extracted from Nigella Sativa seeds and doped with copper to form nanocomposites. A variety technique helped characterize, study, and understand the two compounds structure and properties. Relative to the extracted melanin, copper doping improved the magnetic properties especially at low temperatures.
Ghada Khouqeer+5 more
wiley +1 more source
How habitable are M-dwarf Exoplanets? Modeling surface conditions and exploring the role of melanins in the survival of Aspergillus niger spores under exoplanet-like radiation [PDF]
Exoplanet habitability remains a challenging field due to the large distances separating Earth from other stars. Using insights from biology and astrophysics, we studied the habitability of M-dwarf exoplanets by modeling their surface temperature and flare UV and X-ray doses using the Martian atmosphere as a shielding model.
arxiv +1 more source
Malignant melanoma has the highest mortality rate among skin cancers due to its aggressiveness and metastatic potential, and early diagnosis is important because treatment options are limited. We synthesized a brominated benzamide derivative labeled with 68Ga and evaluated its biological properties as a PET imaging probe.
Dagyeong Hong+9 more
wiley +1 more source
Fungal Melanins and their Potential Applications: A Review
Melanins are complex molecules found in many organisms including bacteria, fungi, plants, and animals that have protective functions against stress. In fungi there are several biochemical routes for their synthesis, and their diversity and structural ...
Sac N. Salgado-Castillo+6 more
doaj +2 more sources
The peculiarities of dynamic current-voltage and charge-voltage loops and transient currents of melanin under pulse hydration [PDF]
Melanin is a biopolymer with unique set of applicable physical and chemical properties. The impact of a moisture-saturated air pulse (~1 s) on dynamic current-voltage (I-V-), charge-voltage (Q-V-) and transient (I-t-) characteristics of fungal melanin thin layers was investigated.
arxiv
The Toxicity of Melanin Precursors
The quinone intermediates resulting from tyrosinase-mediated oxidation of tyrosine were evaluated as sulfhydryl reagent inhibitors of purified calf thymus DNA polymerase alpha in order to determine which of these might be cytotoxic. Dopachrome and an oxidation product of 2,4,5-trihydroxyphenylalanine were relatively ineffective as inhibitors of DNA ...
Sylvia M. Tiffany+2 more
openaire +3 more sources