Results 131 to 140 of about 21,003 (323)
Attività biologica e studi di docking di derivati bis-ammidici dell'acido 5,6- diidrossiindolo-2-carbossilico come inibitori dell'enzima HIV-1 integrasi [PDF]
In un precedente studio, nel tentativo di identificare nuovi inibitori dell'HIV-1 integrasi, è stata da noi considerata la modifica strutturale dell'estere feniletilico dell'acido caffeico I (CAPE), il primo prodotto naturale inibitore dell'IN ...
Angotzi, Gianfranco+9 more
core
THE P-DIMETHYLAMINOBENZALDEHYDE REACTION FOR PYRROLES IN HISTOCHEMISTRY: MELANINS, ENTEROCHROMAFFIN, ZYMOGEN GRANULES, LENS [PDF]
R. D. Lillie
openalex +1 more source
The cell‐in‐shell (CiS) structures are synthesized for Saccharomyces cerevisiae, with the metal–organic complex of Fe3+ and benzenehexacarboxylic acid (Fe3+‐BHC MOC), the nanoshell of which has a unique characteristic of controllable compositional‐transformation to Fe3+‐phosphate in addition to cytocompatibility, cytoprotectability, and degradability ...
Sang Yeong Han+3 more
wiley +1 more source
Mass spectrometry in ocular drug research
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo+6 more
wiley +1 more source
Deciphering the skeletal interoceptive circuitry to control bone homeostasis
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu+7 more
wiley +1 more source
The Role of the Comstock-Kellogg Glands in Egg Tanning in Romalea guttata [PDF]
FreshIy laid eggs of the Eastern Lubber grasshopper, Romalea guttata, are yellow and soft-shelled, but within several hours the eggs become hardened and dark brown. In a similar process, calyx and oviduct secretions, which from the egg pod, become frothy,
Elasser \u2798, Elizabeth A.
core +1 more source
Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah+9 more
wiley +1 more source
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen+7 more
wiley +1 more source
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang+7 more
wiley +1 more source
ABSTRACT Guadua angustifolia var. bicolor Lodoño is a Colombian bamboo species that has shown promising medicinal properties. This study aims to investigate the differences in the chemical composition and biological activity of extracts from two different populations of G. angustifolia var. bicolor, collected in Bauru and Tatuí, Brazil.
João Kazlauckas+2 more
wiley +1 more source