Results 11 to 20 of about 21,945 (222)

Differential Antifungal Activity of Human and Cryptococcal Melanins with Structural Discrepancies [PDF]

open access: yesFrontiers in Microbiology, 2017
Melanin is a pigment found in all biological kingdoms, and plays a key role in protection against ultraviolet radiation, oxidizing agents, and ionizing radiation damage. Melanin exerts an antimicrobial activity against bacteria, fungi, and parasites.
Néstor Correa   +12 more
doaj   +3 more sources

Modeling Fungal Melanin Buildup: Biomimetic Polymerization of 1,8‐Dihydroxynaphthalene Mapped by Mass Spectrometry [PDF]

open access: gold, 2017
Due to the emerging biomedical relevance and technological potential of fungal melanins, and prompted by the virtual lack of information about their structural arrangement, an optimized synthetic protocol has been devised for a potential structural model
Martina Maya Cecchini   +4 more
openalex   +3 more sources

A Straightforward Access to New Amides of the Melanin Precursor 5,6-Dihydroxyindole-2-carboxylic Acid and Characterization of the Properties of the Pigments Thereof

open access: yesMolecules, 2022
We report herein an optimized procedure for preparation of carboxamides of 5,6-dihydroxyindole-2-carboxylic acid (DHICA), the main biosynthetic precursor of the skin photoprotective agents melanins, to get access to pigments with more favorable ...
Rita Argenziano   +3 more
doaj   +1 more source

Fungal melanins differ in planar stacking distances. [PDF]

open access: yesPLoS ONE, 2012
Melanins are notoriously difficult to study because they are amorphous, insoluble and often associated with other biological materials. Consequently, there is a dearth of structural techniques to study this enigmatic pigment.
Arturo Casadevall   +3 more
doaj   +1 more source

Research on the antiviral activity of water-soluble melanin from the pharmaceutical chaga mushroom (Inonotus obliquus) against influenza А virus subtypes H5N1, H3N2 and H1N1pdm09 in experiments in vitro

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2023
Introduction. Influenza A virus is the cause of epidemics and pandemics that severely affect the health and socioeconomic status of the world's population.
Ekaterina I. Filippova   +5 more
doaj   +1 more source

Melanin, melanin "ghosts," and melanin composition in Cryptococcus neoformans [PDF]

open access: yesInfection and Immunity, 1996
Melanin synthesis is associated with virulence for the pathogenic fungus Cryptococcus neoformans. Exposure of nonmelanized C. neoformans 4067 cells to 4 M guanidinium isothiocyanate followed by 6 M HCl at 100 degrees C resulted in complete solubilization of cellular structures. However, exposure of melanized C.
Y, Wang, P, Aisen, A, Casadevall
openaire   +2 more sources

A Melanin-Related Phenolic Polymer with Potent Photoprotective and Antioxidant Activities for Dermo-Cosmetic Applications

open access: yesAntioxidants, 2020
Eumelanins, the dark variant of skin pigments, are endowed with a remarkable antioxidant activity and well-recognized photoprotective properties that have been ascribed to pigment components derived from the biosynthetic precursor 5,6-dihydroxyindole-2 ...
Davide Liberti   +4 more
doaj   +1 more source

The First Homozygote Mutation c.499G>T (Asp167Tyr) in the RPE65 Gene Encoding Retinoid Isomerohydrolase Causing Retinal Dystrophy

open access: yesCurrent Issues in Molecular Biology, 2022
RPE65, an abundant membrane-associated protein present in the retinal pigment epithelium (RPE), is a vital retinoid isomerase necessary for regenerating 11-cis-retinaldehyde from all-trans retinol in the visual cycle.
Mirjana Bjeloš   +4 more
doaj   +1 more source

Genetic and Environmental Factors Influencing the Production of Select Fungal Colorants: Challenges and Opportunities in Industrial Applications

open access: yesJournal of Fungi, 2023
Natural colorants, mostly of plant and fungal origins, offer advantages over chemically synthetic colorants in terms of alleviating environmental pollution and promoting human health.
Lan Lin, Tong Zhang, Jianping Xu
doaj   +1 more source

Melanisation in Boreal Lichens Is Accompanied by Variable Changes in Non-Photochemical Quenching

open access: yesPlants, 2022
Lichens often grow in microhabitats where they absorb more light than they can use for fixing carbon, and this excess energy can cause the formation of harmful reactive oxygen species (ROS).
Nqobile Truelove Ndhlovu   +3 more
doaj   +1 more source

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