Taphonomic experiments reveal authentic molecular signals for fossil melanins and verify preservation of phaeomelanin in fossils. [PDF]
Slater TS+7 more
europepmc +1 more source
Targeting IGF1‐Induced Cellular Senescence to Rejuvenate Hair Follicle Aging
Age‐related increases in IGF‐1 expression in the skin accelerate stem cell exhaustion and senescence by impairing SIRT1 function, ultimately driving hair follicle aging. Conversely, activating SIRT1, clearing senescent cells, or adopting dietary restriction can mitigate excessive IGF‐1 signaling and provide a promising strategy to rejuvenate hair ...
Yang Wang+22 more
wiley +1 more source
13C Nuclear Magnetic Resonance Spectra of Fungal Melanins [PDF]
Francisco Javier González-Vila+3 more
openalex +1 more source
Prevention of Post‐Inflammatory Hyperpigmentation in Skin of Colour: A Systematic Review
ABSTRACT Background/Objectives Post‐inflammatory hyperpigmentation (PIH) impacts all skin tones with a heightened predilection for Fitzpatrick skin types (FST) III‐VI. Preventative measures include pre‐ and post‐intervention approaches, such as sunscreen and corticosteroids. This systematic review aims to summarise the preventative measure outcomes for
Kristie Mar+5 more
wiley +1 more source
De Novo Genome Assembly of Toniniopsis dissimilis (Ramalinaceae, Lecanoromycetes) from Long Reads Shows a Comparatively High Composition of Biosynthetic Genes Putatively Involved in Melanin Synthesis. [PDF]
Gerasimova JV+3 more
europepmc +1 more source
Abstract Purpose To investigate 2‐year changes in macular choroidal thickness (ChT) in children receiving 0.01% atropine eyedrops and its relationship with spherical equivalent refraction (SER) progression and axial length (AL) elongation. Methods A total of 250 myopic children aged 6–16 years (167%–0.01% atropine, 83‐placebo) were enrolled in the ...
Emmanuel Kobia‐Acquah+3 more
wiley +1 more source
Natural pigments derived from plants and microorganisms: classification, biosynthesis, and applications. [PDF]
Tang Q, Li Z, Chen N, Luo X, Zhao Q.
europepmc +1 more source
Aspergillus niger as a cell factory for the production of pyomelanin, a molecule with UV-C radiation shielding activity. [PDF]
Koch SM+10 more
europepmc +1 more source
Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs+12 more
wiley +1 more source