Label‐Free 3D Photoacoustic Imaging of Tumor Organoids for Volumetric Drug Screening
A label‐free organoid photoacoustic imaging (LFOPI) system is developed for precise volumetric drug screening evaluation. As a proof of concept, LFOPI's performance in chemotherapy and immunotherapy drug screening assays are further evaluated. The LFOPI offers unique non‐invasive, label‐free capabilities for tumor organoids, and contributes to the ...
Xiaofei Luo+18 more
wiley +1 more source
The pbrB gene encodes a laccase required for DHN-melanin synthesis in conidia of Talaromyces (Penicillium) marneffei. [PDF]
Talaromyces marneffei (Basionym: Penicillium marneffei) is a significant opportunistic fungal pathogen in patients infected with human immunodeficiency virus in Southeast Asia. T. marneffei cells have been shown to become melanized in vivo.
Ariya Sapmak+3 more
doaj +1 more source
13C nuclear magnetic resonance spectra of fungal melanins [PDF]
3 pages, 1 figures, 2 tables, 14 references.The 13C resonance spectra of fungal melanins from Aspergillus niger, Eurotium echinolatum, and Stachybotrys chartarum are reported.
González-Vila, Francisco Javier+3 more
core
The opportunistic human pathogenic fungus Aspergillus fumigatus produces at least two types of melanin, namely pyomelanin and dihydroxynaphthalene (DHN) melanin.
T. Heinekamp+5 more
semanticscholar +1 more source
A multifunctional anisotropic Au‐Pd heterostructured nanosystem is developed that incorporates a plasmonically enhanced Au‐Pd core, with a shell composed of a biodegradable, Mn‐doped targeting peptide. The nanosystem integrates photothermal, radiotherapeutic, and immunomodulatory functions.
Cheng Chen+8 more
wiley +1 more source
Fungal Melanins and their Potential Applications: A Review
Melanins are complex molecules found in many organisms including bacteria, fungi, plants, and animals that have protective functions against stress. In fungi there are several biochemical routes for their synthesis, and their diversity and structural ...
Sac N. Salgado-Castillo+6 more
doaj +2 more sources
GENES DETERMINING THE SYNTHESIS OF LAVONOID AND MELANIN PIGMENTS IN BARLEY
In addition to the green color caused by chlorophyll, grain and vegetative organs of barley can be colored by compounds of phenolic nature, such as melanins and lavonoids, which include anthocyanins, proanthocyanidins. Due to the wide biological activity
O. Yu. Shoeva+2 more
doaj +1 more source
Polymeric peptide pigments with sequence-encoded properties [PDF]
Melanins are a family of heterogeneous polymeric pigments that provide ultraviolet (UV) light protection, structural support, coloration, and free radical scavenging.
Abzalimov, Rinat R.+14 more
core +2 more sources
Structural Variations Associated with Adaptation and Coat Color in Qinghai‐Tibetan Plateau Cattle
This study reveals the landscape of structural variants in Qinghai‐Tibetan Plateau cattle through long‐read sequencing. Discoveries include metabolic and oxygen‐regulation gene variants, along with a 2‐Mb KIT‐containing inversion and translocations responsible for cattle gray coat. These findings highlight the significant role of structural variants in
Xiaoting Xia+39 more
wiley +1 more source
Condition-dependence of pheomelanin-based coloration in nuthatches Sitta europaea suggests a detoxifying function: implications for the evolution of juvenile plumage patterns [PDF]
Adult-like juvenile plumage patterns often signal genotypic quality to parents. During adulthood, the same patterns often signal quality to mates.
Galván, Ismael
core +1 more source