Results 201 to 210 of about 54,942 (309)

OX40/OX40L modulation: A target for regulating T cells in cutaneous inflammatory disorders

Journal of the European Academy of Dermatology and Venereology, EarlyView.
OX40 and OX40L are a co‐stimulatory immune checkpoint pair. Modulation of this pair impacts multiple immune phenotypes and is an attractive target for immunotherapy in dermatological disorders. Trials are underway with the majority in atopic dermatitis and currently in phase 3 trials.
Aditya K. Gupta, Julia Steriopoulos, Vasiliki Economopoulos, Paradi Mirmirani, Vincent Piguet   +4 more
wiley   +1 more source

RIPOR2 promotes multinucleation of melanoma cells downstream of the RAS/ERK oncogenic pathway. [PDF]

iScience
Wilmerding A, Richard A, Macagno N, Hirsinger E, Gharsalli T, Bellenger L, Naouar N, Gaudy C, Mallet S, Degardin N, Bouteille L, Caruso N, Duprez D, Graba Y, Medjkane S, Etchevers HC, Delfini MC.   +16 more
europepmc   +1 more source

Dynamic colour change predicts movement behaviour in a diadromous fish

Journal of Fish Biology, EarlyView.
Abstract Dynamic changes in colour and pattern facilitate key behavioural functions in animals, particularly camouflage for predator avoidance. However, the benefits of colour change depend on the environmental and behavioural contexts. We tested how colour change interacts with movement behaviour in a freshwater fish by filming individuals in an open ...
Joshua S. Barrow, John R. Morrongiello
wiley   +1 more source

Multiomics Analysis Reveals Distinct Changes in the Cellular Composition of Vulvar Lichen Sclerosus. [PDF]

J Low Genit Tract Dis
Sun X, Liu C, Sun Y, Chen X, Cong Q, Li J.   +5 more
europepmc   +1 more source

Melanoma and Other Melanistic Lesions in Brown Bullhead Ameiurus nebulosus From Waterbodies in the Northeastern United States and Canada: Identification of Risk Factors

Journal of Fish Diseases, EarlyView.
ABSTRACT Melanistic lesions, including non‐raised black areas due to proliferations of melanocytes and melanomacrophages in the dermis and epidermis, as well as raised black areas consistent with melanoma, are described in brown bullhead (BBH) Ameiurus nebulosus from three water bodies in the northeastern United States and Quebec, Canada.
Vicki S. Blazer, Peter Emerson, Matthew Bodnar, Thomas Jones, David R. Russell, Matthew Pehrson, Cheyenne R. Smith, Danielle Cleveland, Mark J. Henderson, Patricia M. Mazik   +9 more
wiley   +1 more source

Bittersweet: how hyperglycemia exacerbates vitiligo progression through the succinate/SUCNR1 axis. [PDF]

J Clin Invest
O'Donnell KG, Le Poole IC.
europepmc   +1 more source

Neural modulation of ocular immunity: Exploring a sympathetic‐macrophage neuroimmune link in the human ciliary body

Journal of Anatomy, EarlyView.
Using microscopy and 3D confocal imaging on seven cadaveric eyes, we identified sympathetic nerves closely associated with β₂‐adrenergic receptor‐expressing macrophages in the human ciliary body (CB). These findings suggest a sympathetic‐macrophage neuroimmune link in the CB, potentially influencing ocular inflammation and degeneration, warranting ...
Tanya S. Karakyriakou, Claire Mackaaij, Mark van Zijverden, Hendrik A. Messal, Jeannette Ossewaarde‐van Norel, Ronald L. A. W. Bleys, Cindy G. J. Cleypool   +6 more
wiley   +1 more source

A diagnostic clue: New onset alopecia sparing white hairs

JAAD Case Reports
Margaret Chen, Lucette Liddell, MD, Robert Brodell, MD   +2 more
doaj   +1 more source

A novel role of erythropoietin in skin pigmentation through melanin production. [PDF]

Sci Rep
Han MA, Kang E, Kwon OH, Kim SY, Moon C, Lee CH.   +5 more
europepmc   +1 more source

Mucosal Melanoma of Head and Neck: A Rare and Aggressive Disease—A Register‐Based Cohort Study

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Mucosal melanomas of the head and neck are rare and often diagnosed in the advanced stage. This study examines the incidence, survival and histology of mucosal melanoma compared to its cutaneous counterpart. Methods This register‐based cohort study reviews head and neck melanomas at Helsinki University Hospital, Finland, from 2002 ...
Sara C. Degerholm, Tuula A. Salo, Matti O. Mauramo   +2 more
wiley   +1 more source