Results 171 to 180 of about 552,068 (289)

Designer Solid Self‐Emulsifying Nanovaccines Enable Dual Modulation of Dendritic Cells and T Cells for Potent Antitumor Immunity

Advanced Science, EarlyView.
A solid self‐emulsifying (SSE) platform is loaded with peptide antigens and CpG to form the SSE vaccine. An ApoE‐enriched corona promotes dendritic cell internalization, enabling antigen presentation and T cell activation. Squalene from the SSE also sensitizes T cells by promoting lipid raft formation.
Xueying Shen, Shiqi Fan, Jia He, Lanqing Luo, Junyao Li, Chengcheng Wu, Kairu Yang, Xiaojun Xia, Rui Kuai   +8 more
wiley   +1 more source

Germline inactivation of tumor suppressor BAP1 is associated with white spotting. [PDF]

J Clin Invest
Njauw CN, Ji Z, Latoni DI, Villa-Gonzalez JM, McCormick S, Kumar R, Usoltsev D, Artomov M, Gan B, Tsao H.   +9 more
europepmc   +1 more source

Lentigo maligna and lentigo maligna melanoma

, 1996
John H Altshuler
openalex   +1 more source

Uso da tomografia por emissão de pósitrons (PET) para identificação precoce de metástases e investigação da eficácia terapêutica da combinação p19Arf e Interferon-Beta em melanoma murino [PDF]

, 2018
Maria Freire
openalex   +1 more source

Supplementary Methods, Figure Legends 1-3 from A Novel Mouse Model for <i>De novo</i> Melanoma

, 2023
Mayuko Y. Kumasaka, Ichiro Yajima, Khaled Hossain, Machiko Iida, Toyonori Tsuzuki, Tamio Ohno, Masahide Takahashi, Masashi Yanagisawa, Masashi Kato   +8 more
openalex   +1 more source

Beyond Catalytic Therapy: Copper‐Paeonol Nanozymes Disrupt Fascin‐Mediated Actin Bundling to Suppress Tumor Growth and Metastasis

Advanced Science, EarlyView.
Copper‐paeonol nanozymes target tumor‐specific reactive oxygen species generation and disrupt fascin‐mediated actin bundling, effectively suppressing tumor growth and metastatic colonization. Abstract Fascin, an actin‐bundling protein universally upregulated in metastatic tumors, drives tumor migration and invasion by promoting filopodia and ...
Peiying Zhang, Huajun Li, Yisen Wang, Jie Xiang, Lei Fan, Shengzhe Zhang, Lizeng Gao, Hua Dai, Juqun Xi   +8 more
wiley   +1 more source

Towards evidence-based policy in melanoma screening and skin self-examination education. [PDF]

J Eur Acad Dermatol Venereol
Ozdemir SO, Shourick J.
europepmc   +1 more source

Chronic lymphatic leukaemia, malignant melanomas and mosquito hypersensitivity

, 1977
S. Lidén, Ove Bäck, Arne Tärnvik
openalex   +2 more sources

Data from A Functional Landscape of Resistance to MEK1/2 and CDK4/6 Inhibition in NRAS-Mutant Melanoma

, 2023
Tikvah K. Hayes, Flora Luo, Ofir Cohen, Amy Goodale, Yenarae Lee, Sasha Pantel, Mukta Bagul, Federica Piccioni, David E. Root, Levi A. Garraway, Matthew Meyerson, Cory M. Johannessen   +11 more
openalex   +1 more source

Tubule‐Derived IFN‐α Promotes GSDMD‐Mediated Macrophage Pyroptosis to Drive Renal Inflammation and Fibrosis Through JAK2/STAT2 Activation

Advanced Science, EarlyView.
Mao and colleagues uncover a STAT2/IRF9‐dependent signaling axis through which tubular epithelial cell (TEC)‐derived IFN‐α induces gasdermin D (GSDMD)‐mediated pyroptosis in macrophages. This TEC‐macrophage feedback loop amplifies renal inflammation and fibrosis, providing mechanistic insight into the progression of chronic kidney disease and revealing
Yiping Xu, Yating Wang, Siming Jiang, Yi Li, Guanglan Li, Yuchu Liu, Siyuan Li, Yiming Zhou, Qinghua Liu, Yi Zhou, Wei Chen, Hongyu Li, Haiping Mao   +12 more
wiley   +1 more source