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Role of Melanopsin in Circadian Responses to Light
Science, 2002Melanopsin has been proposed as an important photoreceptive molecule for the mammalian circadian system. Its importance in this role was tested in melanopsin knockout mice. These mice entrained to a light/dark cycle, phase-shifted after a light pulse, and increased circadian period when light intensity increased.
Norman F, Ruby +6 more
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Responding to Light with Melanopsin
Science's STKE, 2005Certain mammalian retinal ganglion cells that express melanopsin act as photoreceptors that regulate circadian and pupillary responses. Although melanopsin is required for the photosensitivity of these cells, and has been proposed to act as a photopigment, its exact function has been uncertain. Two groups, Qiu et al
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[Pupil and melanopsin photoreception].
Nippon Ganka Gakkai zasshi, 2013The iris is the most anterior portion of the uveal tract. The pupil is round opening near the center of the iris; it is displaced slightly downward and nasally with respect to the center of the cornea. The mammalian iris sphincter is considered to be innervated by cholinergic, and the dilator muscle by adrenergic excitatory nerve fibers, and both ...
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Melanopsin: From a small molecule to brain functions
Neuroscience and Biobehavioral Reviews, 2020Mariusz Duda +2 more
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Opponent melanopsin and S-cone signals in the human pupillary light response
Proceedings of the National Academy of Sciences of the United States of America, 2014Manuel Spitschan +2 more
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Proceedings of the National Academy of Sciences of the United States of America, 2017
Manuel Spitschan +2 more
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Manuel Spitschan +2 more
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Melanopsin and the Intrinsically Photosensitive Retinal Ganglion Cells: Biophysics to Behavior
Neuron, 2019Michael Tri H
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