Multimodal Approach for Recalcitrant Melasma Using Picosecond Laser and Topical JAK Inhibition: A Case Report. [PDF]
J Cosmet DermatolABSTRACT Background Melasma is a chronic hyperpigmentation disorder with high relapse rates, particularly in Fitzpatrick skin types III–V. Increasing evidence implicates cytokine‐driven inflammation and visible light–induced melanogenesis as key contributors to disease persistence.
Ashkanani H +3 more
europepmc +2 more sources
Treatment of Melasma Targeting Dermal-Epidermal Interactions Utilizing High-Intensity, High-Frequency Parallel Ultrasound Beam in Asian Skin. [PDF]
J Cosmet DermatolABSTRACT Background Melasma is a multifactorial disorder, and while treatments aimed at suppressing melanin production and removing excess melanin have demonstrated some efficacy, no definitive therapy has yet been established. Dermal aging is widely recognized as a contributing factor in melasma, and previous studies have demonstrated that the ...
Oku K.
europepmc +2 more sources
Exploring the Effectiveness, Tolerability, and Safety of the Adjunctive Use of Microneedling With Tranexamic Acid in the Treatment of Melasma. [PDF]
J Cosmet DermatolABSTRACT Background Melasma is a chronic pigment disorder associated with significant psychosocial burden. The gold standard triple combination cream is effective but limited by relapse and adverse effects. Tranexamic acid (TXA) and microneedling have independently shown promise in the treatment of melasma, and their combined use may provide enhanced ...
Dhaliwal S, Dhanoa N, Rashid Z.
europepmc +2 more sources
Comment on: Efficacy of Platelet-Rich Plasma Therapy in Melasma Using Microinjections and Microneedling Techniques. [PDF]
J Cosmet DermatolJournal of Cosmetic Dermatology, Volume 25, Issue 3, March 2026.
Wang D, Chen Y, Han Z.
europepmc +2 more sources
Development and validation of a multidimensional questionnaire for evaluating quality of life in melasma (HRQ-melasma) [PDF]
Anais Brasileiros de Dermatologia, 2018 : BACKGROUND: Melasma has a major impact on quality of life. MELASQoL is the only validated specific psychometric instrument to evaluate melasma QoL.
Camila Fernandes Pollo +3 more
doaj +2 more sources
Evaluation of Serum Estrogen, Progesterone, Prolactin and Testosterone in Patients of Melasma
Pakistan Armed Forces Medical Journal, 2023 Objective: To evaluate the estrogen, progesterone, Prolactin and testosterone serum levels in melasma patients. Study Design: Comparative cross-sectional study.
Shamsa Kanwal +5 more
doaj +1 more source
The Professional Medical Journal, 2017 Introduction: Melasma is an acquired, chronic, recurrent symmetricalhypermelanosis which is characterized by brown patches of variable darkness on sun exposedareas of the body primarily on the face.1,2 Melasma is more common in Asians and in peoplewho live in locations that receive high intensity UV radiation.3,4 Melasma is a skin disease ...
Clio Dessinioti, Andreas Katsambas
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Retrospective Study: The Use of Chemical Peeling with A Modified Jessner's in Melasma Patients
Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2016 Background: Melasma is a hipermelanosis that lead to brownish or brownish-grey discoloration on the face. Chemical peeling is one of the additional therapy for melasma. The right indication using modified Jessner's solution give a good result for melasma.
Zada Febrial Effendy +1 more
doaj +1 more source
PLoS ONE, 2022 BackgroundAccording to the literature, pigmentary disorders have a significantly negative impact on a person's health-related quality of life. Moreover, among pigmentary disorders, incidence of melasma ranks high.
Yuan Zhu +5 more
doaj +1 more source
The Profile and Triggering Factors of Melasma Patients: A Retrospective Study
Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2023 Background: Melasma is a skin pigmentation disorder characterized by brownish hyperpigmented lesions with symmetrical distribution and irregular borders.
Putri Brillian Betrista Viorizka +3 more
doaj +1 more source