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Melasma is a common acquired hyperpigmentary disorder of the face. However, the pathogenesis of melasma remains largely unknown and the treatment is still challenging. This article discusses histology of melasma in view of melanin pigmentation with a more in depth question about number of melanocytes and melanophages in dermis of melasma.
H, Young Kang, J-P, Ortonne
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Background: Melasma is an acquired pigmentation disorder of the sun exposed parts of the body, particularly face. It is a significant cosmetic concern for the young adults, which is the most frequently affected age-group. Finding the level of impairment
Sushil Paudel +5 more
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Etiopathogenesis of Melasma [PDF]
Known since ancient times, melasma is notoriously a frequent dyspigmentation disorder characterized by localized, chronic acquired cutaneous hypermelanosis. Despite high frequency, significant negative effects on quality of life and often unsatisfactory results of available treatment, not much research has been performed on the etiopathogenesis of this
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Melasma is an acquired pigmentary disorder characterized by symmetrical hyperpigmented macules on the face. Its pathogenesis is complex and involves the interplay of various factors such as genetic predisposition, ultraviolet radiation, hormonal factors, and drugs.
Rashmi Sarkar +4 more
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Melasma, a chronic pigmentary skin condition mainly affecting the face, remains a challenge despite the availability of several options for treatment. Many melasma patients are not satisfied with treatment outcomes.
Kiran Godse +12 more
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Is Topical Zinc Effective in the Treatment of Melasma? A Double-Blind Randomized Comparative Study [PDF]
Background and ObjectivesZinc plays a role in skin health, and preliminary data have shown its beneficial effects for melasma. We compared the effect of topical zinc with that of hydroquinone as the standard treatment on severity of melasma. Patients and
Eskandari, Yasaman. +5 more
core +1 more source
A Scoping Review on Melasma Treatments and Their Histopathologic Correlates
Melasma is an incredibly common dyschromic disorder, mostly impacting women with skin of color. There are three variants of melasma based on the depth of pathologic involvement: epidermal, mixed, and dermal.
Aurore D. Zhang +5 more
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Psychodermatology of the Female: Hormones, Skin and Mental Health Across the Lifespan
Hormonal transitions across the female lifespan shape skin disease and psychiatric comorbidity through the brain–skin axis and Neuro‐Immuno‐Cutaneous‐Endocrine (NICE) network. This narrative review links puberty, menstruation, pregnancy, postpartum and menopause to dermatologic and psychosocial outcomes.
Sheila Sharifi +4 more
wiley +1 more source
Physiological changes during pregnancy can trigger or worsen dermatological conditions, yet evidence‐based guidance for safe management remains limited. In a cross‐sectional survey of 273 pregnant women, 33.7% reported having a skin disease, and 56% experienced worsening of symptoms.
Frederikke Seeberg +4 more
wiley +1 more source
Background: Melasma is an acquired disease with an unclear etiology. This study aimed to compare the hemoglobin, serum iron, iron-binding capacity, ferritin, zinc, vitamin B12, and vitamin D levels in patients with melasma to those in controls and to ...
Ebru Akal, Mehmet Melikoğlu
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