Results 41 to 50 of about 2,037 (184)

Quality of Life in Patients with Melasma and Its Association with Epidemiological and Clinical Characteristics: A Cross-Sectional Study [PDF]

مجله علوم پزشکی صدرا
Introduction: Melasma is a prevalent pigmentary disorder that often affects quality of life. Prior studies reported inconsistent associations between clinical factors and quality of life in these patients, which highlighted the need for further research ...
Mohammad Mahdi Parvizi, Mozhdeh Sepaskhah, Nasrin Saki, Negin Fazelzadeh Haghighi, Soliman Mohammadi-Samani, Parisa Ghasemiyeh, Fatemeh Karimi, Soodabeh Samimi, Sara Ranjbar, Zahra Bagheri   +9 more
doaj   +1 more source

Efficacy and safety of metformin for melasma treatment: a systematic review and meta-analysis

Frontiers in Pharmacology, 2023
Objective: Metformin has recently been demonstrated to have an anti-melanogenic activity. Nevertheless, clinical evidence of the effectiveness of metformin in melasma is lacking.
Pajaree Mongkhon, Pajaree Mongkhon, Chidchanok Ruengorn, Chidchanok Ruengorn, Ratanaporn Awiphan, Ratanaporn Awiphan, Chabaphai Phosuya, Chabaphai Phosuya, Yongyuth Ruanta, Yongyuth Ruanta, Kednapa Thavorn, Kednapa Thavorn, Kednapa Thavorn, Kednapa Thavorn, Sirinda Jamjanya, Mati Chuamanochan, Mati Chuamanochan, Surapon Nochaiwong, Surapon Nochaiwong   +18 more
doaj   +1 more source

A meta-analysis on the efficacy of tranexamic acid in the treatment of melasma

Pifu-xingbing zhenliaoxue zazhi
The aim of this study was to compare the efficacy of TXA with other therapies for melasma. Melasma is a common acquired skin condition characterized by hypermelanosis, causing light to dark patches, and is the most prevalent in individuals with ...
ALHEJAIRI Rehab, MOHAMMED Abaker Ahmed Alnour Ruaa, ALA'A Suwait Deeb Al Suwait, CHEN Yongfeng   +3 more
doaj   +1 more source

A comparative study of melasma severity after hyperthyroid therapy in hyperthyroid subjects with melasma.

Acta Dermatovenerologica Alpina Pannonica et Adriatica, 2021
INTRODUCTION Melasma, and its variant chloasma, is an acquired and chronic disorder of hyperpigmentation, characterized by symmetrical hypermelanoses of the face. The exact pathogenesis of melasma remains unclear.
B. Nelson, I. B. S. Sitohang, Melani Marissa, Wresti Indriatmi, Wismandari Wisnu   +4 more
semanticscholar   +1 more source

Comparative study of melasma in patients before and after treatment based on lipomics

Lipids in Health and Disease
Background Skin barrier alterations play a crucial function in melasma development. Past researches have demonstrated variations in lipid content between the epidermis of melasma lesions and normal tissues, along with the varied expression of lipid ...
Yuan Zhu, Jinhui Xu, Xiuzu Song, Wenzhong Xiang   +3 more
doaj   +1 more source

Combination of Oral Tranexamic Acid and Glycolic Acid 50% Peel Vs. Oral Tranexamic Acid in  the Treatment of Melasma

Advanced Medical Journal
Background and Objectives: Melasma remains a challenging condition due to the limited efficacy of current treatments. This study aimed to compare the effectiveness and safety of combining oral Tranexamic acid (TXA) with a 50% Glycolic acid peel versus ...
Marya Aurahman, Ali Elethawi
doaj   +1 more source

Are improvements in melasma severity correlated with improvements in quality of life? A systematic review

Dermatologic Therapy, 2021
Dear Editor, Melasma is a hyperpigmentation disorder that predominantly affects the face, resulting in significant impairment in quality of life (QOL).
A. Bailey, Brian Dorus, H. Li, N. Kanigsberg   +3 more
semanticscholar   +1 more source

Efficacy and Safety of 755‐nm Picosecond Alexandrite Laser for Acquired Bilateral Naevus of Ota‐Like Macules (Hori Naevus): A Systematic Review and Meta‐Analysis

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Acquired bilateral naevus of Ota‐like macules (ABNOM), also known as Hori's naevus, is a common dermal melanocytosis causing facial hyperpigmentation. While the 755‐nm Q‐switched alexandrite lasers (QSAL) are traditionally used, they are limited by moderate clearance and substantial risk of post‐inflammatory hyperpigmentation (PIH).
Kangjie R. Chua, Mohammad Ghotmi, Dilip K. Vankayalapati, Ji Young Kim, Konstantinos Baronos, Emma J. B. Nordahl, Alma Sato, Sum‐Yu C. Lee, Hayato Nakanishi, Christian A. Than, Davin Lim   +10 more
wiley   +1 more source

Real‐world evidence for the efficacy and tolerability of an isobutylamido‐thiazolyl‐resorcinol (Thiamidol)‐containing skincare regimen on facial hyperpigmentation and overall skin appearance: A multi‐centre study in 11 European countries

International Journal of Cosmetic Science, EarlyView.
A Thiamidol‐containing skincare regimen showed significant improvement in facial hyperpigmentation in a real‐world study across 11 European countries. The treatment led to a significant reduction in mMASI scores, enhanced overall skin condition and demonstrated high tolerability.
B. Schuster, T. Rogers, C. Vendruscolo, D. Roggenkamp, W. G. Philipp‐Dormston, F. Al‐Niaimi, S. Roussel, N. Kiss, H. Malik, D. Grozeva, K. S. Berger, C. Rauscher, L. Kolbe   +12 more
wiley   +1 more source

Antioxidant activity in melasma

, 2018
Background and Design: Melasma is a common, symmetric hypermelanosis characterized by irregular brown to gray-brown macules on the face. It is frequently associated with pregnancy and oral contraceptive consumption.
Akcay, Yasemin, Ertam, Ilgen, Sozmen, Eser Yildirim, Ozkapu, Tugce, Unal, Idil   +4 more
core   +1 more source