Results 61 to 70 of about 2,037 (184)

Table_1_Short Practical Regimen of Acupuncture for Melasma: A Prospective Cohort Study in a Tertiary Hospital in Thailand.DOCX

, 2021
Background: Acupuncture shows benefits for patients with melasma, although no optimal number of sessions have been determined.Methods: The prospective observational study was conducted in melasma patients who were treated with acupuncture procedures two ...
Krit Pongpirul (5735576), Thanan Supasiri (11644450), Nuntida Salakshna (11644453)   +2 more
core   +1 more source

The Cutaneous Melatoninergic System: Endogenous Biology and Potential for Therapeutic Targeting

Experimental Dermatology, Volume 35, Issue 11, November 2026.
ABSTRACT Melatonin is best known as a pineal hormone that regulates circadian rhythms, but the skin also possesses an intrinsic melatoninergic system capable of local synthesis, metabolism and signalling. This system encompasses classical melatonin receptors, biologically active metabolites, non‐classical signalling pathways and receptor‐independent ...
Ju Hee Han, Hei Sung Kim
wiley   +1 more source

Receptor‐Targeted Niosomal Nanocarriers: Advances, Challenges, and Opportunities in Natural Compound Delivery for Cancer Therapy

Nano Select, Volume 7, Issue 10, October 2026.
Surface‐modified niosomes are introduced as multifunctional nanoparticles for precision tumor treatment that combine hydrophilic and lipophilic drug encapsulation with ligand‐based targeting via antibodies, peptides, transferrin, and folic acid. This modification leads to increased tumor selectivity, facilitates cell entry, and enables enhanced ...
Narges Sahraei, Aryan M. Faraj, Faezeh Molaei, Abolfazl Barzegar   +3 more
wiley   +1 more source

Chlorine Position Governs the Multitarget Bioactivity of Phenylhydrazines: In Vitro Antioxidant, Anti‐Inflammatory, Anti‐Tyrosinase and Antibacterial Evaluation Supported by DFT and Molecular Docking

ChemistrySelect, Volume 11, Issue 37, 6 October 2026.
Positional chlorination emerges as a key determinant of multitarget activity in phenylhydrazines. The para‐chloro derivative H3 shows the strongest anti‐inflammatory response, notable antibacterial activity, favorable ADMET behavior, and high COX‐2 affinity. DFT descriptors and molecular docking rationalize these substitution‐dependent effects, linking
L. Aouachria, S. Issadi, H. Debab, I. Selatnia, A.G. Soliman, K. Metwally, O. M. A. Khamaysa, Han‐seung Lee, Hassane Lgaz   +8 more
wiley   +1 more source

An Updated Insight about Interventional Treatment of Melasma [PDF]

Zagazig University Medical Journal
:Background: Melasma is a highly prevalent hyperpigmentation problem that affects a large percentage of the global population. It is most commonly seen in women and those with Fitzpatrick Skin Types III–VI.
Amany Nassar, Reem Soliman, Hagar Nofal
doaj   +1 more source

Is Topical Zinc Effective in the Treatment of Melasma? A Double-Blind Randomized Comparative Study [PDF]

, 2014
Background and ObjectivesZinc plays a role in skin health, and preliminary data have shown its beneficial effects for melasma. We compared the effect of topical zinc with that of hydroquinone as the standard treatment on severity of melasma. Patients and
Eskandari, Yasaman., Yousefi, Alireza., Omrani, Nooshin., Moini, Amir Mansoor., Zakerzadeh Forooshani, Saeed., Khani Khoozani, Zahra.   +5 more
core  

Efficacy and Safety of an Oral Nutritional (Dietary) Supplement Containing Pinus pinaster Bark Extract and Grape Seed Extract in Combination with a High SPF Sunscreen in the Treatment of Mild-to-Moderate Melasma: A Prospective Clinical Study

Cosmetics, 2019
Background: Melasma is a common hyperpigmentation disorder, characterized by light-to-dark brown patches, usually distributed on sun-exposed areas of the body.
Sonia Aladrén, Aurora Garre, Palmira Valderas-Martínez, Jaime Piquero-Casals, Corinne Granger   +4 more
doaj   +1 more source

Preparation and Characterization of Azelaic Acid‐Loaded Nanofiber Scaffold as Anti‐Acne and Depigmenting Care, Fabricated by Electrospinning Method

Journal of Cosmetic Dermatology, Volume 25, Issue 10, October 2026.
ABSTRACT Objective Acne vulgaris is a common dermatological concern, and conventional topical azelaic acid formulations may have limitations in skin residence time and tolerability. Polymeric nanofiber scaffolds offer a promising platform for topical drug delivery.
Niki Yadegari, Fatemeh Majdi, Nooshafarin Amani, Nasrin Samadi, Farid Abedin Dorkoush, Hamid Akbari Javar   +5 more
wiley   +1 more source

Correlation Between Glutathione Plasma with Degree Severity of Melasma in Balinese Women

Clinical, Cosmetic and Investigational Dermatology, 2020
Introduction Melasma is a condition of hyperpigmentation of the facial skin that increases in prevalence with ageing. The alleged involvement of reactive oxygen species and antioxidants is the basis of the pathology of melasma.
A. A. G. Wiraguna, Embun Dini Hari, I. Gusti Ayu Agung Praharsini   +2 more
semanticscholar   +1 more source

Skin Lightening and Evenness Effects of Oral Supplementation With S‐Acetyl Glutathione in Comparison With Reduced Glutathione: A Double‐Blind, Placebo‐Controlled Clinical Trial

Journal of Cosmetic Dermatology, Volume 25, Issue 10, October 2026.
ABSTRACT S‐Acetyl Glutathione (SAG) is an advanced glutathione derivative designed to improve stability, bioavailability, and efficacy in skin‐lightening applications. Unlike conventional glutathione formulations, SAG offers great cellular uptake and antioxidative properties, making it a promising candidate for managing hyperpigmentation disorders ...
Arie Kusumawardani, Lilik Norawati, Silvia Veronica, Alamanda Murasmita, Ervina Rosmarwati   +4 more
wiley   +1 more source