Results 31 to 40 of about 111,238 (263)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Effects of Melissa officinalis Alcoholic Extract on Kidney Tissue and Apoptosis Gene Expression in a Wistar Rat Model With Spinal Cord Injury [PDF]

open access: yesPharmaceutical and Biomedical Research
Background: Spinal cord injury (SCI) is a severe neurological condition that can cause widespread inflammation, affecting vital organs, such as the kidneys. The kidneys are essential for filtering waste and maintaining blood components.
Ali salehi
doaj  

The genesis of “Into the snowstorm” by Debra A. Castillo & Melissa Castillo-Planas

open access: yesAltre Modernità, 2019
The genesis of “Into the snowstorm” by Debra A.
Melissa Castillo Planas
doaj   +1 more source

Melissa officinalis: A potent herb against EMS induced mutagenicity in mice

open access: yesCaryologia, 2020
Melissa officinalis (L) is used traditionally for different medical purposes such as tonic, antispasmodic, carminative, diaphoretic, surgical dressing for wounds, sedative hypnotic, strengthening the memory and relief of stress induced headache.The ...
Hilal Ahmad Ganaie   +2 more
doaj   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

open access: yesFEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow   +12 more
wiley   +1 more source

The Survey on the Changes of Oil Compounds of Medicinal and Edible Plants Sterilized with Gamma Radiation

open access: yesJournal of Medicinal Plants, 2007
Background: One of the essential problems of using medicinal plants which are mostly collected from the wild is their fungus and microbial infections. Nowadays, exposing the plants to Gamma radiation apparently removes the problem.
MH Salehi Surmaghi   +3 more
doaj  

The Many Dimensions of Diet Breadth: Phytochemical, Genetic, Behavioral, and Physiological Perspectives on the Interaction between a Native Herbivore and an Exotic Host. [PDF]

open access: yesPLoS ONE, 2016
From the perspective of an herbivorous insect, conspecific host plants are not identical, and intraspecific variation in host nutritional quality or defensive capacity might mediate spatially variable outcomes in plant-insect interactions.
Joshua G Harrison   +9 more
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

The Antiviral Effect of Melissa Botany Extract on Proliferation of Rotavirus Causing Acute Gastroenteritis

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2015
Background and Objectives: Being widespread in all over the world, rotaviruses are known as the leading cause of acute gastroenteritis in forms of epidemic and endemic in infants and young children from 2-24 months of age.
Shahram Zehtabian
doaj  

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