Results 1 to 10 of about 70 (66)
Deciphering the therapeutical potentials of rosmarinic acid
Scientific Reports, 2022 AbstractLemon balm is herbal tea used for soothing stomach cramps, indigestion, and nausea. Rosmarinic acid (RA) is one of its chemical constituents known for its therapeutic potentials against cancer, inflammatory and neuronal diseases such as the treatment of neurofibromatosis or prevention from Alzheimer’s diseases (AD).
Sally El Kantar +10 more
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Rosmarinic Acid – Pharmaceutical and Clinical Aspects [PDF]
Planta Medica, 2016 The biosynthesis and biotechnological production of Rosmarinic acid, a phenolic ester that is widespread in the plant kingdom, has been widely investigated. This compound has shown many remarkable biological and pharmacological activities, which have led to its pharmaceutical and analytical development, as well as clinical studies, which are summarized
Solomon K S, Amoah +3 more
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Biogenesis of rosmarinic acid in Mentha [PDF]
Biochemical Journal, 1970 The biogenesis of rosmarinic acid (α-O-caffeoyl-3,4-dihydroxyphenyl-lactic acid), the second most common ester of caffeic acid in the plant kingdom, was studied in Mentha arvense and Mentha piperita. Administration of 14C-labelled compounds showed that, whereas the caffeoyl moiety was formed from phenylalanine via cinnamic acid and p-coumaric acid, the
B E, Ellis, G H, Towers
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Serum Albumin Modulates the Bioactivity of Rosmarinic Acid [PDF]
Journal of Medicinal Food, 2018 Rosmarinic acid (RA) is a phenolic compound with biological activity. The objective of the present study was to investigate whether this compound kept its biological activity in the presence of proteins. For this purpose, bovine serum albumin (BSA) was used as a model protein, and the capacity of the RA to inhibit acetylcholinesterase (AChE) and affect
Brito, Elsa +7 more
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Magnetite Microspheres for the Controlled Release of Rosmarinic Acid
Pharmaceutics, 2022 Since cancer incidence is constantly increasing, novel and more efficient treatment methods that overcome the current limitations of chemotherapy are continuously explored. In this context, the aim of the present study was to investigate the potential of two types of magnetite microspheres as drug delivery vehicles for the controlled release of ...
Cristina Chircov +4 more
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Biomedical features and therapeutic potential of rosmarinic acid
Archives of Pharmacal Research, 2022 For decades, the use of secondary metabolites of various herbs has been an attractive strategy in combating human diseases. Rosmarinic acid (RA) is a bioactive phenolic compound commonly found in plants of Lamiaceae and Boraginaceae families. RA is biosynthesized using amino acids tyrosine and phenylalanine via enzyme-catalyzed reactions.
Saba Noor +7 more
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Rosmarinic Acid–Human Pharmacokinetics and Health Benefits [PDF]
Planta Medica, 2020 AbstractRosmarinic acid is a phenolic compound commonly found in the Lamiaceae (Labiateae) plant species. It is considered responsible for a wide spectrum of biological and pharmacological activities of plants containing this compound. The aim of the current review is to present the fate of rosmarinic acid inside the human body, explained through ...
Maja Hitl +3 more
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Metabolic modeling of Rosmarinic acid biosynthetic pathway [PDF]
Bioinformation, 2010 Rosmarinic acid (RA) is an ester of caffeic acid and 3, 4-dihydroxyphenyllacticacid. It is commonly found in Coleus blumei, Salvia officinalis, Melissa officinalis and Rosmarinus officinalis. The biosynthesis of RA starts with precursor molecules L-phenylalanine and L-tyrosine.
Shanthy, Sundaram +2 more
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Therapeutic Potential of Rosmarinic Acid: A Comprehensive Review [PDF]
Applied Sciences, 2019 Naturally occurring food-derived active ingredients have received huge attention for their chemopreventive and chemotherapy capabilities in several diseases. Rosmarinic acid (RA) is a caffeic acid ester and a naturally-occurring phenolic compound in a number of plants belonging to the Lamiaceae family, such as Rosmarinus officinalis (rosemary) from ...
Muhammad Nadeem +15 more
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Effect of Rosmarinic Acid on Experimental Diabetic Nephropathy [PDF]
Basic & Clinical Pharmacology & Toxicology, 2011 Abstract: Connective tissue growth factor (CTGF) plays a pathogenic role in diabetic nephropathy (DN). Rosmarinic acid (RA) is a naturally occurring phenolic acid. This study was conducted to investigate the efficacy of RA on DN and to elucidate the potential mechanism.
Wang-Lin, Jiang +4 more
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