Results 11 to 20 of about 12,222 (161)

The chemoprotective hormetic effects of rosmarinic acid [PDF]

open access: yesOpen Medicine
Rosmarinic acid is a polyphenol found in numerous fruits and vegetables, consumed in supplement form, and tested in numerous clinical trials for therapeutic applications due to its putative chemopreventive properties. Rosmarinic acid has been extensively
Calabrese Edward J.   +7 more
doaj   +4 more sources

Application of Rosmarinic Acid with Its Derivatives in the Treatment of Microbial Pathogens

open access: yesMolecules, 2023
The emergence of the antimicrobial resistance phenomena on and the harmful consequences of the use of antibiotics motivate the necessity of innovative antimicrobial therapies, while natural substances are considered a promising alternative.
Ourdia-Nouara Kernou   +3 more
doaj   +3 more sources

Rosmarinic Acid Inhibits PRV Replication by Regulating Oxidative Stress Through the Nrf2 Signaling Pathway [PDF]

open access: yesAnimals
Pseudorabies (PR) is an acute and highly contagious disease caused by the pseudorabies virus (PRV). This virus has a wide range of susceptible hosts and has caused major economic losses to the global swine industry.
Ruifei Li   +7 more
doaj   +2 more sources

Effect of rosmarinic acid on microbial activity, antioxidant capacity, and metabolite profiles of fermented milk containing Lactiplantibacillus plantarum [PDF]

open access: yesFood Chemistry: X
This study aimed to elucidate how rosmarinic acid (0, 0.01, 0.03 g/100 mL) affects the microbial activity, antioxidant capacity, and metabolite profiles of fermented milk co-cultured with Lactiplantibacillus plantarum and commercial starter.
Hongwei Yin   +4 more
doaj   +2 more sources

Antioxidant Activity of Rosmarinic Acid Extracted and Purified from Mentha piperita [PDF]

open access: yesArchives of Razi Institute, 2021
Rosmarinic acid was obtained from methanolic extract of Mentha piperita L. under a reflux condenser. The current study aimed to evaluate the in vitro antioxidant activities and rosmarinic acid levels of the methanol extracts of M. piperita.
F. E. H Aldoghachi   +2 more
doaj   +1 more source

Involvement of Organic Anion Transporters in the Pharmacokinetics and Drug Interaction of Rosmarinic Acid

open access: yesPharmaceutics, 2021
We investigated the involvement of drug transporters in the pharmacokinetics of rosmarinic acid in rats as well as the transporter-mediated drug interaction potential of rosmarinic acid in HEK293 cells overexpressing clinically important solute carrier ...
Yun Ju Kang   +5 more
doaj   +1 more source

Rosmarinic Acid, a Bioactive Phenolic Compound, Inhibits Glutamate Release from Rat Cerebrocortical Synaptosomes through GABAA Receptor Activation

open access: yesBiomolecules, 2021
Rosmarinic acid, a major component of rosemary, is a polyphenolic compound with potential neuroprotective effects. Asreducing the synaptic release of glutamate is crucial to achieving neuroprotectant’s pharmacotherapeutic effects, the effect of ...
Che-Chuan Wang   +3 more
doaj   +1 more source

Rosmarinic acid ameliorates HCl-induced cystitis in rats.

open access: yesPLoS ONE, 2023
Shiso (Perilla frutescens var crispa f. purprea) is a traditional medicinal herb that exerts anti-inflammatory effects and alleviates lower urinary tract symptoms. In this study, we examined the effects of rosmarinic acid, a major polyphenol in shiso, on
Naoya Kitamura   +3 more
doaj   +1 more source

Short Chain (≤C4) Esterification Increases Bioavailability of Rosmarinic Acid and Its Potency to Inhibit Vascular Smooth Muscle Cell Proliferation

open access: yesFrontiers in Pharmacology, 2021
Rosmarinic acid is a natural phenolic acid and active compound found in many culinary plants, such as rosemary, mint, basil and perilla. Aiming to improve the pharmacokinetic profile of rosmarinic acid and its activity on vascular smooth muscle cell ...
Tina Blažević   +7 more
doaj   +1 more source

Investigation of antioxidant effects of rosmarinic acid on liver, lung and kidney in rats: a biochemical and histopathological study

open access: yesFolia Morphologica, 2020
Background: The aim of the study was to investigate the protective effects of rosmarinic acid in rats exposed to hepatic ischaemia/reperfusion (I/R) injury.
A. Oğuz   +9 more
doaj   +1 more source

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