Results 21 to 30 of about 12,302 (189)

Protective Effects of Rosmarinic Acid on Testicular Torsion-Detorsion in an Animal Model [PDF]

open access: yesIranian Journal of Veterinary Surgery, 2022
Testicular torsion is a disorder that may cause infertility or subfertility in males. Rosmarinic acid (RA) is a natural polyphenol with potent antioxidant effects that its protective effects in ischemia/reperfusion (I/R) injury in the hepatic, renal ...
Abbas Raisi   +2 more
doaj   +1 more source

Serum Albumin Modulates the Bioactivity of Rosmarinic Acid [PDF]

open access: yesJournal of Medicinal Food, 2018
Rosmarinic acid (RA) is a phenolic compound with biological activity. The objective of the present study was to investigate whether this compound kept its biological activity in the presence of proteins. For this purpose, bovine serum albumin (BSA) was used as a model protein, and the capacity of the RA to inhibit acetylcholinesterase (AChE) and affect
Brito, Elsa   +7 more
openaire   +3 more sources

Unveiling the interaction profile of rosmarinic acid and its bioactive substructures with serum albumin

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2020
Rosmarinic acid, a phytochemical compound, bears diverse pharmaceutical profile. It is composed by two building blocks: caffeic acid and a salvianic acid unit.
Christina Papaemmanouil   +6 more
doaj   +1 more source

Rosmarinic Acid–Human Pharmacokinetics and Health Benefits [PDF]

open access: yesPlanta Medica, 2020
AbstractRosmarinic acid is a phenolic compound commonly found in the Lamiaceae (Labiateae) plant species. It is considered responsible for a wide spectrum of biological and pharmacological activities of plants containing this compound. The aim of the current review is to present the fate of rosmarinic acid inside the human body, explained through ...
Maja Hitl   +3 more
openaire   +2 more sources

Pharmacokinetics, Safety and Tolerability of Melissa officinalis Extract which Contained Rosmarinic Acid in Healthy Individuals: A Randomized Controlled Trial.

open access: yesPLoS ONE, 2015
The aim of this study was to evaluate the safety, tolerability and pharmacokinetics of single dose of Melissa officinalis extract which contained rosmarinic acid, including food-effects in healthy individuals.
Moeko Noguchi-Shinohara   +7 more
doaj   +1 more source

Magnetite Microspheres for the Controlled Release of Rosmarinic Acid

open access: yesPharmaceutics, 2022
Since cancer incidence is constantly increasing, novel and more efficient treatment methods that overcome the current limitations of chemotherapy are continuously explored. In this context, the aim of the present study was to investigate the potential of two types of magnetite microspheres as drug delivery vehicles for the controlled release of ...
Cristina Chircov   +4 more
openaire   +3 more sources

Derivatization of Rosmarinic Acid Enhances its in vitro Antitumor, Antimicrobial and Antiprotozoal Properties

open access: yesMolecules, 2019
On its own, rosmarinic acid possesses multiple biological activities such as anti-inflammatory, antimicrobial, cardioprotective and antitumor properties, and these are the consequence of its ROS scavenging and inhibitory effect on inflammation.
Silvia Bittner Fialová   +9 more
doaj   +1 more source

Biomedical features and therapeutic potential of rosmarinic acid

open access: yesArchives of Pharmacal Research, 2022
For decades, the use of secondary metabolites of various herbs has been an attractive strategy in combating human diseases. Rosmarinic acid (RA) is a bioactive phenolic compound commonly found in plants of Lamiaceae and Boraginaceae families. RA is biosynthesized using amino acids tyrosine and phenylalanine via enzyme-catalyzed reactions.
Saba Noor   +7 more
openaire   +2 more sources

Rosmarinic acid ameliorates hypoxia/ischemia induced cognitive deficits and promotes remyelination

open access: yesNeural Regeneration Research, 2020
Rosmarinic acid, a common ester extracted from Rosemary, Perilla frutescens, and Salvia miltiorrhiza Bunge, has been shown to have protective effects against various diseases.
Man Li   +10 more
doaj   +1 more source

Production of rosmarinic acid in hairy root cultures of Salvia reuterana [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2016
It was the first time that hairy roots were initiated from Salvia reuterana by infection with Agrobacterium rhizogenes strain ATTC 15834. Confirmatory studies were carried out by direct detection of inserted T-DNA by the polymerase chain reaction.
Reza Norouzi   +3 more
doaj   +1 more source

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