Results 31 to 40 of about 12,222 (161)
Evaluation of Rosmarinic Acid Attenuation Effect on Endoplasmic Reticulum Stress in Swiss-type Mice Affected With Nonalcoholic Steatohepatiti [PDF]
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2023 Background and Objectives: Nonalcoholic steatohepatitis is a severe liver disease characterized by excess lipid accumulation (steatosis) and inflammation in the liver.
Tahereh Komeili-Movahhed +2 more
doaj
Protective Effects of Rosmarinic Acid on Testicular Torsion-Detorsion in an Animal Model [PDF]
Iranian Journal of Veterinary Surgery, 2022 Testicular torsion is a disorder that may cause infertility or subfertility in males. Rosmarinic acid (RA) is a natural polyphenol with potent antioxidant effects that its protective effects in ischemia/reperfusion (I/R) injury in the hepatic, renal ...
Abbas Raisi +2 more
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Rosmarinic Acid–Human Pharmacokinetics and Health Benefits [PDF]
Planta Medica, 2020 AbstractRosmarinic acid is a phenolic compound commonly found in the Lamiaceae (Labiateae) plant species. It is considered responsible for a wide spectrum of biological and pharmacological activities of plants containing this compound. The aim of the current review is to present the fate of rosmarinic acid inside the human body, explained through ...
Maja Hitl +3 more
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Magnetite Microspheres for the Controlled Release of Rosmarinic Acid
Pharmaceutics, 2022 Since cancer incidence is constantly increasing, novel and more efficient treatment methods that overcome the current limitations of chemotherapy are continuously explored. In this context, the aim of the present study was to investigate the potential of two types of magnetite microspheres as drug delivery vehicles for the controlled release of ...
Cristina Chircov +4 more
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 Rosmarinic acid, a phytochemical compound, bears diverse pharmaceutical profile. It is composed by two building blocks: caffeic acid and a salvianic acid unit.
Christina Papaemmanouil +6 more
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Biomedical features and therapeutic potential of rosmarinic acid
Archives of Pharmacal Research, 2022 For decades, the use of secondary metabolites of various herbs has been an attractive strategy in combating human diseases. Rosmarinic acid (RA) is a bioactive phenolic compound commonly found in plants of Lamiaceae and Boraginaceae families. RA is biosynthesized using amino acids tyrosine and phenylalanine via enzyme-catalyzed reactions.
Saba Noor +7 more
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PLoS ONE, 2015 The aim of this study was to evaluate the safety, tolerability and pharmacokinetics of single dose of Melissa officinalis extract which contained rosmarinic acid, including food-effects in healthy individuals.
Moeko Noguchi-Shinohara +7 more
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Molecules, 2019 On its own, rosmarinic acid possesses multiple biological activities such as anti-inflammatory, antimicrobial, cardioprotective and antitumor properties, and these are the consequence of its ROS scavenging and inhibitory effect on inflammation.
Silvia Bittner Fialová +9 more
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Production of rosmarinic acid in hairy root cultures of Salvia reuterana [PDF]
مجله بیوتکنولوژی کشاورزی, 2016 It was the first time that hairy roots were initiated from Salvia reuterana by infection with Agrobacterium rhizogenes strain ATTC 15834. Confirmatory studies were carried out by direct detection of inserted T-DNA by the polymerase chain reaction.
Reza Norouzi +3 more
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Metabolic modeling of Rosmarinic acid biosynthetic pathway [PDF]
Bioinformation, 2010 Rosmarinic acid (RA) is an ester of caffeic acid and 3, 4-dihydroxyphenyllacticacid. It is commonly found in Coleus blumei, Salvia officinalis, Melissa officinalis and Rosmarinus officinalis. The biosynthesis of RA starts with precursor molecules L-phenylalanine and L-tyrosine.
Shanthy, Sundaram +2 more
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