Results 51 to 60 of about 12,302 (189)

Protective Contribution of Rosmarinic Acid in Rosemary Extract Against Copper-Induced Oxidative Stress

open access: yesAntioxidants
Rosemary extract (Rosmarinus officinalis) is a natural source of bioactive compounds with significant antioxidant properties. Among these, rosmarinic acid is celebrated for its potent antioxidant, anti-inflammatory, antimicrobial, and neuroprotective ...
Arian Kola   +3 more
doaj   +1 more source

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat   +7 more
wiley   +1 more source

Solvation Free Energy Simulation for Rosmarinic Acid Extraction from Orthosiphon stamineus

open access: yesMethods and Protocols, 2019
This study was aimed to extract rosmarinic acid from Orthosiphon stamineus Benth. (Lamiaceae) in high yield. The mixture of chloroform−ethyl acetate (70:30) was chosen as the solvent system because rosmarinic acid gave the lowest solvation free ...
Cher Haan Lau, Lee Suan Chua
doaj   +1 more source

Does rosmarinic acid underestimate as an experimental cardiovascular drug? [PDF]

open access: yesActa Cirurgica Brasileira, 2013
PURPOSE: The rationale of the present review is to analize the activity of Rosmarinus officinalis in the the cardiovascular system METHODS: A MEDLINE database search (from January 1970 to December 2011) using only rosmarinic acid as searched term.
Ferreira, Luciana Garros   +6 more
openaire   +5 more sources

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

open access: yesPrecision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

Rosmarinic acid prevents fibrillization and diminishes vibrational modes associated to β sheet in tau protein linked to Alzheimer’s disease

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2017
Alzheimer’s disease is a common tauopathy where fibril formation and aggregates are the hallmark of the disease. Efforts targeting amyloid-β plaques have succeeded to remove plaques but failed in clinical trials to improve cognition; thus, the current ...
Alberto Cornejo   +9 more
doaj   +1 more source

Rosemary metabolite carnosic acid opens Kv1.1 via its voltage sensor and corrects Kv1.1‐linked episodic ataxia in mice

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder caused primarily by loss‐of‐function mutations in the voltage‐gated potassium channel Kv1.1 (KCNA1). Small molecules that restore Kv1.1 activity hold promise as targeted therapies for EA1, yet current pharmacological strategies remain limited ...
Rían W. Manville   +6 more
wiley   +1 more source

Yeast Extract and Silver Nitrate Induce the Expression of Phenylpropanoid Biosynthetic Genes and Induce the Accumulation of Rosmarinic Acid in Agastache rugosa Cell Culture

open access: yesMolecules, 2016
The present study aimed to investigate the role of yeast extract and silver nitrate on the enhancement of phenylpropanoid pathway genes and accumulation of rosmarinic acid in Agastache rugosa cell cultures.
Woo Tae Park   +7 more
doaj   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

open access: yesJournal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed   +6 more
wiley   +1 more source

Response of Melissa officinalis subsp. officinalis seedlings to Fe3O4‐NPs under in vitro conditions: physiological, biochemical and molecular analyses

open access: yesPlant Biology, EarlyView.
Iron oxide nanoparticles influence the growth, antioxidant capacity, and gene activity of Melissa officinalis subsp. officinalis plants in vitro, revealing their potential as modulators of secondary metabolism. Abstract Application of iron oxide nanoparticles (NP) (Fe3O4‐NPs) in plant biotechnology presents new opportunities for enhancing metabolic ...
E. Bektaş   +5 more
wiley   +1 more source

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