Lichen Depsides and Tridepsides: Progress in Pharmacological Approaches
Journal of Fungi (Basel, Switzerland), 2023 Depsides and tridepsides are secondary metabolites found in lichens. In the last 10 years, there has been a growing interest in the pharmacological activity of these compounds.
Pradeep Kumar Divakar +2 more
exaly +6 more sources
Lichen-Derived Diffractaic Acid Inhibited Dengue Virus Replication in a Cell-Based System [PDF]
Molecules, 2023 Dengue is a mosquito-borne flavivirus that causes 21,000 deaths annually. Depsides and depsidones of lichens have previously been reported to be antimicrobials. In this study, our objective was to identify lichen-derived depsides and depsidones as dengue
Naphat Loeanurit +10 more
doaj +2 more sources
Genome Mining-Guided Discovery of Two New Depsides from Talaromyces sp. HDN1820200 [PDF]
Marine DrugsDepsides and their derivatives are a class of polyketides predominantly found in fungal extracts. Herein, a silent nonreducing polyketide synthase (TalsA)-containing gene cluster, which was identified from the Antarctic sponge-derived fungus Talaromyces ...
Xiao Zhang +7 more
doaj +2 more sources
Metabolites, 2021 Fungi represent a huge reservoir of structurally diverse bio-metabolites. Although there has been a marked increase in the number of isolated fungal metabolites over the past years, many hidden metabolites still need to be discovered.
Alaa Sirwi +2 more
exaly +3 more sources
Biosynthetic gene cluster synteny: Orthologous polyketide synthases in Hypogymnia physodes, Hypogymnia tubulosa, and Parmelia sulcata [PDF]
MicrobiologyOpen, 2023 Lichens are symbiotic associations consisting of a photobiont (algae or cyanobacteria) and a mycobiont (fungus), which together generate a variety of unique secondary metabolites.
Nadim Ahmad +6 more
doaj +2 more sources
It Is Not All about Alkaloids—Overlooked Secondary Constituents in Roots and Rhizomes of Gelsemium sempervirens (L.) J.St.-Hil [PDF]
PlantsGelsemium sempervirens (L.) J.St.-Hil. is an evergreen shrub occurring naturally in North and Middle America. So far, more than 120 alkaloids have been identified in this plant in addition to steroids, coumarins and iridoids, and its use in traditional ...
Lilo K. Mailänder +5 more
doaj +2 more sources
Citrus reticulata Blanco: A Review on Chemical Composition and Biological Activities. [PDF]
Chem BiodiversThis review compiles chemical information and biological activities from 49 studies on Citrus reticulata. The fruit peels stand out for their high content of methoxylated monoterpenes and flavonoids with antioxidant, anti‐inflammatory, and antimicrobial activities.
Castro JWG +3 more
europepmc +2 more sources
Identification of Secondary Metabolites from the Lichen Hypotrachyna enderythraea (Zahlbr.) Hale by HPLC-ESI-MS/MS [PDF]
MoleculesIn this study, sixteen secondary metabolites, including two chromones, four dibenzofurans, three lipids, three depsides, two aromatic compounds, a quinone, and a terpene, were detected in the methanol:acetone (1:1 v/v) extract of the lichen Hypotrachyna ...
Fernando Carrasco +10 more
doaj +2 more sources
Biosynthesis of the C-Glycosylated Depside Arenicolin B. [PDF]
ChembiochemAbstractWe uncovered the biosynthetic pathway of the C‐glycosylated depside arenicolin B from Phialomyces arenicola through genome mining, heterologous reconstitution and biochemical characterization. The biosynthetic gene cluster (BGC) of arenicolin B is comprised of a HRPKS, a NRPKS, and a C‐glycosyltransferase.
Johnson CW +4 more
europepmc +4 more sources
Efficient Production of Some Bioactive Depsides and Simple Phenolic Acids by Microshoots of Aronia × Prunifolia (Purple Aronia) Agitated Cultures as the Result of Feeding Strategy with Four Different Biogenetic Precursors [PDF]
MoleculesA precursor feeding strategy was used for the first time in agitated microshoot cultures of Aronia × prunifolia. This strategy involved the addition of biogenetic precursors of simple phenolic acids (phenylalanine, cinnamic acid, and benzoic acid) and ...
Paweł Kubica +3 more
doaj +2 more sources