Rosarugosides A and D from Rosa rugosa Flower Buds: Their Potential Anti-Skin-Aging Effects in TNF-α-Induced Human Dermal Fibroblasts [PDF]
This present study investigated the anti-skin-aging properties of Rosa rugosa. Initially, phenolic compounds were isolated from a hot water extract of Rosa rugosa’s flower buds. Through repeated chromatography (column chromatography, MPLC, and prep HPLC),
Kang Sub Kim +6 more
doaj +2 more sources
Efficient Production of Some Bioactive Depsides and Simple Phenolic Acids by Microshoots of Aronia × Prunifolia (Purple Aronia) Agitated Cultures as the Result of Feeding Strategy with Four Different Biogenetic Precursors [PDF]
A precursor feeding strategy was used for the first time in agitated microshoot cultures of Aronia × prunifolia. This strategy involved the addition of biogenetic precursors of simple phenolic acids (phenylalanine, cinnamic acid, and benzoic acid) and ...
Paweł Kubica +3 more
doaj +2 more sources
Imbricaric acid and perlatolic acid: multi-targeting anti-inflammatory depsides from Cetrelia monachorum. [PDF]
In vitro screening of 17 Alpine lichen species for their inhibitory activity against 5-lipoxygenase, microsomal prostaglandin E2 synthase-1 and nuclear factor kappa B revealed Cetrelia monachorum (Zahlbr.) W.L. Culb. & C.F. Culb.
Sarah K Oettl +17 more
doaj +3 more sources
QSAR Analysis of Lichen Depsides and Derivatives: Electronic Descriptors as Predictors of Antioxidant Activity via PLS-1 [PDF]
The antioxidant activity of natural and semi-synthetic depsides and benzofurans—including R-(+)-usnic acid (1), dibenzoyl usnic acid (2), atranorin (3), 2,4-bis(benzoyloxy)atranorin (4), 4-O-methyl atranorin (5), decarboxythamnolic acid (6), thamnolic ...
Patricia Mollinedo +3 more
doaj +2 more sources
Cytotoxic and cytostatic activity of orcinol-type depsides of lichens [PDF]
Lichens synthesize unique secondary metabolites, most of which are not found in other living organisms. More than 800 such metabolites are known, which can be found in various parts of the lichen thallus.
I. A. Prokopyev +7 more
doaj +2 more sources
Depsides: lichen metabolites active against hepatitis C virus. [PDF]
A thorough phytochemical study of Stereocaulon evolutum was conducted, for the isolation of structurally related atranorin derivatives. Indeed, pilot experiments suggested that atranorin (1), the main metabolite of this lichen, would interfere with the ...
Thi Huyen Vu +6 more
doaj +2 more sources
Synthesis of the lichen depsides pseudocyphellarin A and B
The total synthesis of the fully substituted lichen depsides, pseudocyphellarin A (3-hydroxy-4-methoxycarbonyl-2,5,6-trimethylphenyl 3-formyl-2,4-dihydroxy-5,6-dimethylbenzoate) (1) and pseudocyphellarin B (3-hydroxy-4-methoxycarbonyl-2,5,6-trimethylphenyl 2,4-dihydroxy-3-hydroxymethyl-5,6-dimethylbenzoate) (2) is described.
JA Elix, L Lajide
openaire +2 more sources
Unveiling the therapeutic potential of Lobaria extract and its depsides/depsidones in combatting Aβ42 peptides aggregation and neurotoxicity in Alzheimer’s disease [PDF]
Background: The development of effective inhibitors that can inhibit amyloid β (Aβ) peptides aggregation and promote neurite outgrowth is crucial for the possible treatment of Alzheimer’s disease (AD).
Meixia Yang +15 more
doaj +2 more sources
New reagents for the synthesis of depsides
Lichen depsides have now been synthesized by making use of two reagents, dicyclohexyl-carbodiimide (DCC) and trifluoroacetic anhydride. Methyl evernate, methyl lecanorate and evernic acid have been prepared in satisfactory yields.
S. Neelakantan +2 more
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Synthesis of para -olivetol depsides
The unambiguous synthesis of the lichen depsides, anziaic, perlatolic, 2'- O -methylanziaic, 2- O - methylperlatolic, 2'- O -methylperlatolic, 4- O -demethylplanaic, planaic, imbricaric and stenosporic acids is reported. Where necessary the phenolic and carboxy groups of the intermediate phenols were protected by O -benzylation until after the depside ...
JA Elix
openaire +2 more sources

