The Fumarprotocetraric Acid Inhibits Tau Covalently, Avoiding Cytotoxicity of Aggregates in Cells [PDF]
Neurodegenerative disorders, including Tauopathies that involve tau protein, base their pathological mechanism on forming proteinaceous aggregates, which has a deleterious effect on cells triggering an inflammatory response.
Camila González +5 more
doaj +10 more sources
Fumarprotocetraric acid and geraniin were identified as novel inhibitors of human respiratory syncytial virus infection in vitro [PDF]
IntroductionRespiratory syncytial virus (RSV) remains a major international public health concern. However, disease treatment is limited to preventive care with monoclonal antibodies and supportive care.
Chao Wang +15 more
doaj +8 more sources
Two New Fumarprotocetraric Acid Lactones Identified and Characterized by UHPLC-PDA/ESI/ORBITRAP/MS/MS from the Antarctic Lichen Cladonia metacorallifera [PDF]
Lichens are symbiotic organisms between algae and fungi, which are makers of secondary compounds named as lichen substances. Hyphenated techniques have significantly helped natural product chemistry, especially UHPLC/ESI/MS/MS in the identification ...
Beatriz Sepúlveda +4 more
doaj +3 more sources
Effects of Fumarprotocetraric Acid, a Depsidone from the Lichen Cladonia verticillaris, on Tyrosinase Activity [PDF]
Lichens are widely distributed around the world. Their phenolic compounds, consisting mainly of depsides and depsidones, have been extensively studied for important biological activities.
Luiz Fabrício Gardini Brandão +6 more
doaj +6 more sources
The allelopathic activity of the different extracts of the lichen Cladonia verticillaris and fumarprotocetraric acid on the early growth of A cepa (IPA 6) seedlings depends on their chemical composition and concentration, respectively.
A. M. Yano-Melo +2 more
doaj +5 more sources
The Genus Cetraria s. str.—A Review of Its Botany, Phytochemistry, Traditional Uses and Pharmacology [PDF]
The genus Cetraria s. str. (Parmeliaceae family, Cetrarioid clade) consists of 15 species of mostly erect brown or greenish yellow fruticose or subfoliose thallus.
Marta Sánchez +4 more
doaj +2 more sources
Oribatid mites like lichens—feeding preferences among three Cladonia species with different chemistry [PDF]
Lichens in general and members of the genus Cladonia in particular are known for their repertoire of chemical substances. These substances have been attributed various roles, including a role in the defence against herbivores.
Věra Vtípilová +5 more
doaj +2 more sources
The phylogeny and taxonomy of Violella (Tephromelataceae, lichenized Ascomycota), including a new species from China [PDF]
Violella yunnanensis C. J. Zhong & L. Hu is described as new to science. It is characterized by its esorediate, areolate to weakly warted thallus, hymenium heavily pigmented with Fucatus-violet pigment, brownish inner ascospore walls, and its ...
Chun-jiao Zhong, Zun-tian Zhao, Ling Hu
doaj +4 more sources
Cyclodextrin-Based Systems of Cetraria islandica Extracts: A Novel Approach to Improve Solubility and Biological Activity of Lichen-Derived Natural Products [PDF]
Cetraria islandica (L.) Ach. (CI) is a lichen from the Parmeliaceaea family used in medicine. However, the low solubility of CI secondary metabolites in water limits the application of lichen extract and compounds.
Elżbieta Studzińska-Sroka +5 more
doaj +2 more sources
Optimizing the Extraction of Polyphenols from Different Edible Lichens Using Response Surface Methodology and the Determination of Their Mineral and Antibacterial Properties [PDF]
This study employed response surface methodology for the first-time optimization of the ultrasound-assisted extraction (UAE) of the total phenolic content (TPC) and ABTS from edible lichens, including Evernia divaricata, Evernia prunastri, Pseudevernia ...
Kubra Ozkan +8 more
doaj +2 more sources

