Rosarugosides A and D from Rosa rugosa Flower Buds: Their Potential Anti-Skin-Aging Effects in TNF-α-Induced Human Dermal Fibroblasts [PDF]
PlantsThis present study investigated the anti-skin-aging properties of Rosa rugosa. Initially, phenolic compounds were isolated from a hot water extract of Rosa rugosa’s flower buds. Through repeated chromatography (column chromatography, MPLC, and prep HPLC),
Kang Sub Kim +6 more
doaj +2 more sources
QSAR Analysis of Lichen Depsides and Derivatives: Electronic Descriptors as Predictors of Antioxidant Activity via PLS-1 [PDF]
AntioxidantsThe antioxidant activity of natural and semi-synthetic depsides and benzofurans—including R-(+)-usnic acid (1), dibenzoyl usnic acid (2), atranorin (3), 2,4-bis(benzoyloxy)atranorin (4), 4-O-methyl atranorin (5), decarboxythamnolic acid (6), thamnolic ...
Patricia Mollinedo +3 more
doaj +2 more sources
Lichen and Its Microbiome as an Untapped Source of Anti-Biofilm Compounds. [PDF]
Chem BiodiversLichens and their associated fungi give rise to the evaluation of several extracts and compounds against biofilms. ABSTRACT Lichen substances have been first described in the 1870s, and around 10 000 compounds have been isolated and characterized. Most of them have been evaluated for their activity on planktonic microorganisms (bacteria and fungi ...
Millot M +4 more
europepmc +2 more sources
Biosynthesis of Depsides, Depsidones, and Diphenyl Ethers from Fungi and Lichens
Asian Journal of Organic ChemistryDepsides are natural products derived from (poly)phenolic acid derivatives connected by ester bonds. Recent research has revealed crucial molecular mechanisms and distinctive enzymatic chemistry underlying the biosynthesis of depsides, as well as related natural products, such as depsidones and diphenyl ethers.
Yudai Matsuda, Qiaolin Ji
exaly +2 more sources
Unveiling the therapeutic potential of Lobaria extract and its depsides/depsidones in combatting Aβ42 peptides aggregation and neurotoxicity in Alzheimer’s disease [PDF]
Frontiers in PharmacologyBackground: The development of effective inhibitors that can inhibit amyloid β (Aβ) peptides aggregation and promote neurite outgrowth is crucial for the possible treatment of Alzheimer’s disease (AD).
Meixia Yang +15 more
doaj +2 more sources
Lichen Polyphenolic Compounds for the Eradication of Candida albicans Biofilms
Frontiers in Cellular and Infection Microbiology, 2021 Lichens, due to their symbiotic nature (association between fungi and algae), constitute a chemical factory of original compounds. Polyphenolic compounds (depsides and depsidones) are the main constituents of lichens and are exclusively biosynthesized by
Marion Girardot +8 more
doaj +1 more source
Fermentation, 2023 Lactic acid (LA) fermentation of dog’s mercury (M. perennis L.) herbal parts was investigated in samples inoculated with either Lactobacteria (Lactobacillus plantarum and Pediococcus pentosaceus, LBF) or whey (WF).
Peter Lorenz +10 more
doaj +1 more source
A Candidate Gene Cluster for the Bioactive Natural Product Gyrophoric Acid in Lichen-Forming Fungi
Microbiology Spectrum, 2022 Natural products of lichen-forming fungi are structurally diverse and have a variety of medicinal properties. Despite this, they have limited implementation in industry mostly because the corresponding genes are unknown for most of their natural products.
Garima Singh +6 more
doaj +1 more source
Biomolecules, 2020 Cancer is a serious health burden on global societies. The discovery and development of new anti-cancer therapies remains a challenging objective. Although it has been shown that lichen secondary metabolites may be potent sources for new anti-cancer ...
Ari Satia Nugraha +10 more
doaj +1 more source