Results 11 to 20 of about 1,481 (197)
Lichen Depsides and Tridepsides: Progress in Pharmacological Approaches
Depsides and tridepsides are secondary metabolites found in lichens. In the last 10 years, there has been a growing interest in the pharmacological activity of these compounds.
Isabel Ureña-Vacas +2 more
exaly +7 more sources
Fungi represent a huge reservoir of structurally diverse bio-metabolites. Although there has been a marked increase in the number of isolated fungal metabolites over the past years, many hidden metabolites still need to be discovered.
Sabrin R M Ibrahim +2 more
exaly +4 more sources
Genome Mining-Guided Discovery of Two New Depsides from Talaromyces sp. HDN1820200 [PDF]
Depsides and their derivatives are a class of polyketides predominantly found in fungal extracts. Herein, a silent nonreducing polyketide synthase (TalsA)-containing gene cluster, which was identified from the Antarctic sponge-derived fungus Talaromyces ...
Xiao Zhang +7 more
doaj +3 more sources
Cancer is a serious health burden on global societies. The discovery and development of new anti-cancer therapies remains a challenging objective. Although it has been shown that lichen secondary metabolites may be potent sources for new anti-cancer ...
Ari Satia Nugraha +10 more
doaj +2 more sources
Lichen-Derived Diffractaic Acid Inhibited Dengue Virus Replication in a Cell-Based System [PDF]
Dengue is a mosquito-borne flavivirus that causes 21,000 deaths annually. Depsides and depsidones of lichens have previously been reported to be antimicrobials. In this study, our objective was to identify lichen-derived depsides and depsidones as dengue
Naphat Loeanurit +10 more
doaj +2 more sources
Synthesis of Further Lichen Depsides
The unambiguous total synthesis of 18 lichen depsides has been achieved by the condensation of an appropriately substituted orsellinic acid and protected phenol in the key step, followed by subsequent deprotection and/or secondary reduction. The natural occurrence of the first meta-depside involving substitution at the 5??-position of the B-ring has ...
JA Elix +6 more
openaire +2 more sources
Biosynthetic gene cluster synteny: Orthologous polyketide synthases in Hypogymnia physodes, Hypogymnia tubulosa, and Parmelia sulcata [PDF]
Lichens are symbiotic associations consisting of a photobiont (algae or cyanobacteria) and a mycobiont (fungus), which together generate a variety of unique secondary metabolites.
Nadim Ahmad +6 more
doaj +2 more sources
It Is Not All about Alkaloids—Overlooked Secondary Constituents in Roots and Rhizomes of Gelsemium sempervirens (L.) J.St.-Hil [PDF]
Gelsemium sempervirens (L.) J.St.-Hil. is an evergreen shrub occurring naturally in North and Middle America. So far, more than 120 alkaloids have been identified in this plant in addition to steroids, coumarins and iridoids, and its use in traditional ...
Lilo K. Mailänder +5 more
doaj +2 more sources
By investigating of the roots of Salvia miltiorrhiza, which is one of the most widely used Chinese herbs, we used phytochemical methods successfully to obtain twelve depsides: four depsides (1⁻4) that were previously undescribed, along with eight ...
Qinghao Jin +9 more
doaj +2 more sources
Identification of Secondary Metabolites from the Lichen Hypotrachyna enderythraea (Zahlbr.) Hale by HPLC-ESI-MS/MS [PDF]
In this study, sixteen secondary metabolites, including two chromones, four dibenzofurans, three lipids, three depsides, two aromatic compounds, a quinone, and a terpene, were detected in the methanol:acetone (1:1 v/v) extract of the lichen Hypotrachyna ...
Fernando Carrasco +10 more
doaj +2 more sources

