Results 11 to 20 of about 1,590 (200)

Anti-cancer Evaluation of Depsides Isolated from Indonesian Folious Lichens: Physcia millegrana, Parmelia dilatata and Parmelia aurulenta

Biomolecules, 2020
Cancer is a serious health burden on global societies. The discovery and development of new anti-cancer therapies remains a challenging objective. Although it has been shown that lichen secondary metabolites may be potent sources for new anti-cancer ...
Ari Satia Nugraha, Tinton Agung Laksono, Lilla Nur Firli, Chintya Permata Zahky Sukrisno Putri, Dwi Koko Pratoko, Zulfikar Zulfikar, Ludmilla Fitri Untari, Hendris Wongso, Jacob M. Lambert, Carolyn T. Dillon, Paul A. Keller   +10 more
doaj   +2 more sources

Thermal Decomposition of Lichen Depsides

Zeitschrift für Naturforschung B, 1989
The thermal decomposition of the following lichen depsides has been described: lecanoric acid, gyrophoric acid, evernic acid, perlatolic acid, planaic acid, confluentic acid, atranorin, 4-O-de-methylbarbatic acid, and sekikaic acid. Main reaction products are decarboxylated compounds, phenolic units, rearranged depsides, and xanthones. Triethylammonium
Huneck, Siegfried, Schmidt, Jürgen, Tabacchi, Raffaele   +2 more
openaire   +3 more sources

Four New Depsides Isolated from Salvia miltiorrhiza and Their Significant Nerve-Protective Activities

Molecules, 2018
By investigating of the roots of Salvia miltiorrhiza, which is one of the most widely used Chinese herbs, we used phytochemical methods successfully to obtain twelve depsides: four depsides (1⁻4) that were previously undescribed, along with eight ...
Qinghao Jin, Xinyi Hu, Yanping Deng, Jinjun Hou, Min Lei, Hongjian Ji, Jing Zhou, Hua Qu, Wanying Wu, Dean Guo   +9 more
doaj   +2 more sources

Lichen-Derived Bioactive Compounds in Diabetes and Cardiovascular Risk: Experimental Evidence, Mechanisms, and Translational Challenges [PDF]

Biomedicines
Cardiometabolic disorders arise from interconnected metabolic, inflammatory, oxidative, mitochondrial, and vascular abnormalities. Lichens produce structurally diverse secondary metabolites, including depsides, depsidones, dibenzofurans, anthraquinones ...
Alfredo Torres-Benítez, Carlo Acierno, Davide Nilo, Roberta Cutellè, Karla Troncoso-Monsalve, Sebastián Aburto-Urriaga, Francisco Novoa-Sánchez, Ferdinando Carlo Sasso, Vincenzo Russo, Alfredo Caturano   +9 more
doaj   +2 more sources

Imbricaric acid and perlatolic acid: multi-targeting anti-inflammatory depsides from Cetrelia monachorum. [PDF]

PLoS ONE, 2013
In vitro screening of 17 Alpine lichen species for their inhibitory activity against 5-lipoxygenase, microsomal prostaglandin E2 synthase-1 and nuclear factor kappa B revealed Cetrelia monachorum (Zahlbr.) W.L. Culb. & C.F. Culb.
Sarah K Oettl, Jana Gerstmeier, Shafaat Y Khan, Katja Wiechmann, Julia Bauer, Atanas G Atanasov, Clemens Malainer, Ezzat M Awad, Pavel Uhrin, Elke H Heiss, Birgit Waltenberger, Daniel Remias, Johannes M Breuss, Joel Boustie, Verena M Dirsch, Hermann Stuppner, Oliver Werz, Judith M Rollinger   +17 more
doaj   +2 more sources

Cytotoxic and cytostatic activity of orcinol-type depsides of lichens [PDF]

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова
Lichens synthesize unique secondary metabolites, most of which are not found in other living organisms. More than 800 such metabolites are known, which can be found in various parts of the lichen thallus.
I. A. Prokopyev, U. A. Kremenetskaya, O. S. Shemchuk, P. K. Kozhukhov, O. E. Molchanov, D. N. Maistrenko, K. N. Semenov, V. V. Sharoyko   +7 more
doaj   +2 more sources

Rosarugosides A and D from Rosa rugosa Flower Buds: Their Potential Anti-Skin-Aging Effects in TNF-α-Induced Human Dermal Fibroblasts [PDF]

Plants
This present study investigated the anti-skin-aging properties of Rosa rugosa. Initially, phenolic compounds were isolated from a hot water extract of Rosa rugosa’s flower buds. Through repeated chromatography (column chromatography, MPLC, and prep HPLC),
Kang Sub Kim, So-Ri Son, Yea Jung Choi, Yejin Kim, Si-Young Ahn, Dae Sik Jang, Sullim Lee   +6 more
doaj   +2 more sources

Unveiling the therapeutic potential of Lobaria extract and its depsides/depsidones in combatting Aβ42 peptides aggregation and neurotoxicity in Alzheimer’s disease [PDF]

Frontiers in Pharmacology
Background: The development of effective inhibitors that can inhibit amyloid β (Aβ) peptides aggregation and promote neurite outgrowth is crucial for the possible treatment of Alzheimer’s disease (AD).
Meixia Yang, Meixia Yang, Caishan Yan, Dusadee Ospondpant, Dusadee Ospondpant, Lisong Wang, Shengying Lin, Shengying Lin, Wai Lun Tang, Wai Lun Tang, Tina Tingxia Dong, Tina Tingxia Dong, Penger Tong, Qin Xu, Karl Wah Keung Tsim, Karl Wah Keung Tsim   +15 more
doaj   +2 more sources

Deciphering the biosynthetic pathways of lichen acids. [PDF]

New Phytol
Summary Depsides and depsidones are polyketide‐derived lichen acids widely distributed in lichen thalli, yet the biosynthetic gene clusters (BGCs) responsible for their production remain poorly understood. To address this gap, we investigated the diversity and evolutionary relationships of polyketide BGCs in lichens.
Kim W, Shishido TK, Pham HT, Kang KB, Liu R, Wahlsten M, Collemare J, Park H, Oh SO, Ha HH, Kim H, Hur JS.   +11 more
europepmc   +2 more sources

The aquastatin biosynthetic gene cluster encodes a versatile polyketide synthase capable of synthesising heteromeric depsides with diverse alkyl side chains. [PDF]

Chem Sci
Depsides have garnered substantial interest due to the diverse biological activities exhibited by members of this class. Among these are the antibacterial aquastatins, glycosylated heteromeric depsides formed through the condensation of orsellinic acid ...
Sbaraini N, Crombie A, Kalaitzis JA, Vuong D, Bracegirdle J, Windsor F, Lau A, Chen R, Tan YP, Lacey A, Lacey E, Piggott AM, Chooi YH.   +12 more
europepmc   +3 more sources