Results 1 to 10 of about 49,752 (253)

UHPLC-MS/MS-based untargeted metabolite profiling of Lyme neuroborreliosis [PDF]

open access: yesScientific Reports
The diagnosis of Lyme neuroborreliosis (LNB) requires the demonstration of intrathecal synthesis of Borrelia antibodies in a patient’s cerebrospinal fluid (CSF), which involves the invasive procedure of a lumbar puncture.
Ilari Kuukkanen   +8 more
doaj   +5 more sources

Grape Lipidomics: An Extensive Profiling thorough UHPLC-MS/MS Method [PDF]

open access: yesMetabolites, 2021
Lipids play many essential roles in living organisms, which accounts for the great diversity of these amphiphilic molecules within the individual lipid classes, while their composition depends on intrinsic and extrinsic factors.
Domenico Masuero   +7 more
doaj   +4 more sources

Determination of lesinurad in rat plasma by a UHPLC–MS/MS assay [PDF]

open access: yesChemistry Central Journal, 2017
Lesinurad is an oral inhibitor of urate-anion exchanger transporter 1 and has been approved by the US Food and Drug Administration for combination therapy with a xanthine oxidase inhibitor for the treatment of hyperuricemia associated with refractory ...
Xiao-Yang Zhou   +6 more
doaj   +3 more sources

Determination of Paraquat in Arabidopsis Tissues and Protoplasts by UHPLC-MS/MS

open access: yesBio-Protocol, 2023
Paraquat is a cost-effective herbicide, widely used in many countries, that can induce severe oxidative stress in photosynthetic tissues. Studying plant herbicide resistance or antioxidant stress mechanisms requires determining the cellular paraquat ...
Mingming Zhao   +5 more
doaj   +3 more sources

Dynamic profiling of intact glucosinolates in radish by combining UHPLC-HRMS/MS and UHPLC-QqQ-MS/MS

open access: yesFrontiers in Plant Science, 2023
Glucosinolates (GSLs) and their degradation products in radish confer plant defense, promote human health, and generate pungent flavor. However, the intact GSLs in radish have not been investigated comprehensively yet.
Zhengming Qiu   +2 more
exaly   +3 more sources

Determination of 69 Pesticide Residues in 42 Batches of Platycodonis Radix and Dietary Risk Assessment Using Combined QuEChERS with GC-MS/MS and UHPLC-MS/MS [PDF]

open access: yesFoods
This study aimed to establish a rapid analytical method for the determination of 69 pesticide residues in Platycodonis Radix using GC-MS/MS and UHPLC-MS/MS, as well as carry out a dietary risk assessment on 42 batches of Platycodonis Radix samples ...
Jing Ma   +4 more
doaj   +2 more sources

Determination of iohexol by capillary blood microsampling and UHPLC-MS/MS

open access: yesJournal of Pharmaceutical Analysis, 2019
One of the most important tools used to evaluate kidney function in the context of chronic kidney disease or other renal function related pathologies is the exploration of glomerular filtration rate (GFR).
Valentin Ion   +6 more
doaj   +4 more sources

Simultaneous Determination of Structurally Diverse Compounds in Different Fangchi Species by UHPLC-DAD and UHPLC-ESI-MS/MS

open access: yesMolecules, 2013
Two bisbenzylisoquinoline alkaloids, two morphine alkaloids, one aporphine alkaloid, syringaresinol and aristolochic acid І were selected as marker compounds and simultaneously analyzed using an ultra-high pressure liquid chromatography-diode array ...
Lee Kang Ro
exaly   +3 more sources

Determination of imidacloprid in beehive samples by UHPLC-MS/MS

open access: yesMicrochemical Journal, 2018
Abstract Imidacloprid is a systemic insecticide belonging to the neonicotinoid family. It was the first neonicotinoid introduced in the mid-1990s, and since then, its use has grown rapidly to control pests in a variety of agricultural crops. Several studies have shown that neonicotinoids translocate to the nectar and pollen of treated plants, which ...
Maria Rosa Repetti, Julieta Merke
exaly   +3 more sources

Development and Validation of a UHPLC-MS/MS Method for Ciprofol Detection in Plasma: Application in Clinical Pharmacokinetic Studies [PDF]

open access: yesDrug Design, Development and Therapy
Jiaxi Zhu,1,2,* Ying Cao,2,* Xingan Zhang,2 Bo Xu2 1The First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, 510515, People’s Republic of China; 2Department of Anesthesiology, General Hospital of Southern ...
Zhu J, Cao Y, Zhang X, Xu B
doaj   +2 more sources

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