UHPLC-MS/MS-based untargeted metabolite profiling of Lyme neuroborreliosis [PDF]
The diagnosis of Lyme neuroborreliosis (LNB) requires the demonstration of intrathecal synthesis of Borrelia antibodies in a patient’s cerebrospinal fluid (CSF), which involves the invasive procedure of a lumbar puncture.
Ilari Kuukkanen +8 more
doaj +5 more sources
Grape Lipidomics: An Extensive Profiling thorough UHPLC-MS/MS Method [PDF]
Lipids play many essential roles in living organisms, which accounts for the great diversity of these amphiphilic molecules within the individual lipid classes, while their composition depends on intrinsic and extrinsic factors.
Domenico Masuero +7 more
doaj +4 more sources
Determination of lesinurad in rat plasma by a UHPLC–MS/MS assay [PDF]
Lesinurad is an oral inhibitor of urate-anion exchanger transporter 1 and has been approved by the US Food and Drug Administration for combination therapy with a xanthine oxidase inhibitor for the treatment of hyperuricemia associated with refractory ...
Xiao-Yang Zhou +6 more
doaj +3 more sources
Determination of Paraquat in Arabidopsis Tissues and Protoplasts by UHPLC-MS/MS
Paraquat is a cost-effective herbicide, widely used in many countries, that can induce severe oxidative stress in photosynthetic tissues. Studying plant herbicide resistance or antioxidant stress mechanisms requires determining the cellular paraquat ...
Mingming Zhao +5 more
doaj +3 more sources
Dynamic profiling of intact glucosinolates in radish by combining UHPLC-HRMS/MS and UHPLC-QqQ-MS/MS
Glucosinolates (GSLs) and their degradation products in radish confer plant defense, promote human health, and generate pungent flavor. However, the intact GSLs in radish have not been investigated comprehensively yet.
Zhengming Qiu +2 more
exaly +3 more sources
Determination of 69 Pesticide Residues in 42 Batches of Platycodonis Radix and Dietary Risk Assessment Using Combined QuEChERS with GC-MS/MS and UHPLC-MS/MS [PDF]
This study aimed to establish a rapid analytical method for the determination of 69 pesticide residues in Platycodonis Radix using GC-MS/MS and UHPLC-MS/MS, as well as carry out a dietary risk assessment on 42 batches of Platycodonis Radix samples ...
Jing Ma +4 more
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Determination of iohexol by capillary blood microsampling and UHPLC-MS/MS
One of the most important tools used to evaluate kidney function in the context of chronic kidney disease or other renal function related pathologies is the exploration of glomerular filtration rate (GFR).
Valentin Ion +6 more
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Two bisbenzylisoquinoline alkaloids, two morphine alkaloids, one aporphine alkaloid, syringaresinol and aristolochic acid І were selected as marker compounds and simultaneously analyzed using an ultra-high pressure liquid chromatography-diode array ...
Lee Kang Ro
exaly +3 more sources
Determination of imidacloprid in beehive samples by UHPLC-MS/MS
Abstract Imidacloprid is a systemic insecticide belonging to the neonicotinoid family. It was the first neonicotinoid introduced in the mid-1990s, and since then, its use has grown rapidly to control pests in a variety of agricultural crops. Several studies have shown that neonicotinoids translocate to the nectar and pollen of treated plants, which ...
Maria Rosa Repetti, Julieta Merke
exaly +3 more sources
Development and Validation of a UHPLC-MS/MS Method for Ciprofol Detection in Plasma: Application in Clinical Pharmacokinetic Studies [PDF]
Jiaxi Zhu,1,2,* Ying Cao,2,* Xingan Zhang,2 Bo Xu2 1The First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, 510515, People’s Republic of China; 2Department of Anesthesiology, General Hospital of Southern ...
Zhu J, Cao Y, Zhang X, Xu B
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