UHPLC-MS/MS-based untargeted metabolite profiling of Lyme neuroborreliosis [PDF]
Scientific ReportsThe diagnosis of Lyme neuroborreliosis (LNB) requires the demonstration of intrathecal synthesis of Borrelia antibodies in a patient’s cerebrospinal fluid (CSF), which involves the invasive procedure of a lumbar puncture.
Ilari Kuukkanen +8 more
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Grape Lipidomics: An Extensive Profiling thorough UHPLC-MS/MS Method [PDF]
Metabolites, 2021 Lipids play many essential roles in living organisms, which accounts for the great diversity of these amphiphilic molecules within the individual lipid classes, while their composition depends on intrinsic and extrinsic factors.
Domenico Masuero +7 more
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Determination of lesinurad in rat plasma by a UHPLC–MS/MS assay [PDF]
Chemistry Central Journal, 2017 Lesinurad is an oral inhibitor of urate-anion exchanger transporter 1 and has been approved by the US Food and Drug Administration for combination therapy with a xanthine oxidase inhibitor for the treatment of hyperuricemia associated with refractory ...
Xiao-Yang Zhou +6 more
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Determination of Paraquat in Arabidopsis Tissues and Protoplasts by UHPLC-MS/MS
Bio-Protocol, 2023 Paraquat is a cost-effective herbicide, widely used in many countries, that can induce severe oxidative stress in photosynthetic tissues. Studying plant herbicide resistance or antioxidant stress mechanisms requires determining the cellular paraquat ...
Mingming Zhao +5 more
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Determination of 69 Pesticide Residues in 42 Batches of Platycodonis Radix and Dietary Risk Assessment Using Combined QuEChERS with GC-MS/MS and UHPLC-MS/MS [PDF]
FoodsThis study aimed to establish a rapid analytical method for the determination of 69 pesticide residues in Platycodonis Radix using GC-MS/MS and UHPLC-MS/MS, as well as carry out a dietary risk assessment on 42 batches of Platycodonis Radix samples ...
Jing Ma +4 more
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Determination of iohexol by capillary blood microsampling and UHPLC-MS/MS
Journal of Pharmaceutical Analysis, 2019 One of the most important tools used to evaluate kidney function in the context of chronic kidney disease or other renal function related pathologies is the exploration of glomerular filtration rate (GFR).
Valentin Ion +6 more
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Development of a novel UHPLC-MS/MS method for the determination of ochratoxin A in tea [PDF]
Heliyon, 2021 The mycotoxin Ochratoxin A (OTA) is responsible for producing many effects on human and animal health. In this work, the evaluation of the presence of OTA in tea beverage samples consisted of extraction and preconcentration through the solidification of a floating organic drop (DLLME-SFO) combined with an additional octadecyl silane clean-up step.
Luis Dante Martinez, Soledad Cerutti
exaly +6 more sources
Molecules, 2013 Two bisbenzylisoquinoline alkaloids, two morphine alkaloids, one aporphine alkaloid, syringaresinol and aristolochic acid І were selected as marker compounds and simultaneously analyzed using an ultra-high pressure liquid chromatography-diode array ...
Jongki Hong, Kang Ro Lee, Lee Kang Ro
exaly +3 more sources
Development and Validation of a UHPLC-MS/MS Method for Ciprofol Detection in Plasma: Application in Clinical Pharmacokinetic Studies [PDF]
Drug Design, Development and TherapyJiaxi Zhu,1,2,* Ying Cao,2,* Xingan Zhang,2 Bo Xu2 1The First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, 510515, People’s Republic of China; 2Department of Anesthesiology, General Hospital of Southern ...
Zhu J, Cao Y, Zhang X, Xu B
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Determination of α-hydroxy acids in cosmetics by UHPLC-MS/MS
Shanghai yufang yixueObjectiveTo establish a UHPLC-MS/MS quantitative method for the determination of glucuronic acid， tartaric acid， glycolic acid， malic acid， lactic acid， citric acid， DL-2-hydroxybutyric acid sodium， mandelic acid， benzilic acid， hydroxycaprylic acid ...
RU Ge +5 more
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