Results 11 to 20 of about 49,542 (253)

Dynamic profiling of intact glucosinolates in radish by combining UHPLC-HRMS/MS and UHPLC-QqQ-MS/MS

open access: yesFrontiers in Plant Science, 2023
Glucosinolates (GSLs) and their degradation products in radish confer plant defense, promote human health, and generate pungent flavor. However, the intact GSLs in radish have not been investigated comprehensively yet.
Chenghuan Yan   +14 more
doaj   +1 more source

A Strategy for Identification and Structural Characterization of Compounds from Plantago asiatica L. by Liquid Chromatography-Mass Spectrometry Combined with Ion Mobility Spectrometry

open access: yesMolecules, 2022
Plantago asiatica L. (PAL) as a medicinal and edible plant is rich in chemical compounds, which makes the systematic and comprehensive characterization of its components challenging.
Hongxue Gao   +5 more
doaj   +1 more source

Pharmacokinetics and Metabolism Study of Deep-Sea-Derived Butyrolactone I in Rats by UHPLC–MS/MS and UHPLC–Q-TOF-MS

open access: yesMarine Drugs, 2021
Butyrolactone I (BTL-I) is a butanolide isolated from the deep-sea-derived fungus, Aspergillus sp. It provides a potential new target for the prevention and treatment of food allergies.
Liang Wu   +3 more
doaj   +1 more source

Recent Developments Toward Integrated Metabolomics Technologies (UHPLC-MS-SPE-NMR and MicroED) for Higher-Throughput Confident Metabolite Identifications

open access: yesFrontiers in Molecular Biosciences, 2021
Metabolomics has emerged as a powerful discipline to study complex biological systems from a small molecule perspective. The success of metabolomics hinges upon reliable annotations of spectral features obtained from MS and/or NMR. In spite of tremendous
Rajarshi Ghosh   +11 more
doaj   +1 more source

Determination of Antiviral Drugs and Their Metabolites Using Micro-Solid Phase Extraction and UHPLC-MS/MS in Reversed-Phase and Hydrophilic Interaction Chromatography Modes

open access: yesMolecules, 2021
Two new ultra-high performance liquid chromatography (UHPLC) methods for analyzing 21 selected antivirals and their metabolites were optimized, including sample preparation step, LC separation conditions, and tandem mass spectrometry detection.
Luboš Fical   +8 more
doaj   +1 more source

Characterization of URB Series Synthetic Cannabinoids by HRMS and UHPLC–MS/MS

open access: yesPharmaceuticals, 2023
A large number of synthetic cannabinoids are included in new psychoactive substances (NPS) and constitute an open research area in analytical pharmaceutical and toxicology when methods are needed to unambiguously identify these substances and their ...
Marco Agostini   +4 more
doaj   +1 more source

Ultra-high performance liquid chromatography-MS/MS (UHPLC-MS/MS) in practice: analysis of drugs and pharmaceutical formulations

open access: yesFuture Journal of Pharmaceutical Sciences, 2019
Background UHPLC-MS/MS is connected in various research facilities for the qualitative and quantitative investigation of a pharmaceutical substance, pharmaceutical items, and biological specimen.
Ravsaheb H. Rathod   +3 more
doaj   +1 more source

Correlation between quality and geographical origins of Leonuri Herba revealed by the qualitative fingerprint profiling and quantitative determination of chemical components

open access: yesChinese Medicine, 2022
Background Leonuri Herba (Yimucao) is a very common Chinese herbs for treating menstrual and maternal diseases for thousands of years in China. However, the herb collected in different origins was easily found in the markets which induce the unstable ...
Kelly Yinching Lam   +5 more
doaj   +1 more source

Application of chromatographic methods for quality control of cannabinoid impurities in products containing Cannabidiol [PDF]

open access: yesPharmacia
Strict quality control of impurities in legitimate cannabidiol products and in cannabis “novel foods” is necessary due to the increased health risks from side effects associated with these impurities.
Dobrina Tsvetkova   +2 more
doaj   +3 more sources

Determination by UHPLC – UV – MS of polyphenol content of Amaranthus retroflexus

open access: yesNotulae Botanicae Horti Agrobotanici Cluj-Napoca, 2023
Having a very large area globally, the genus Amaranthus has been known since ancient times and used as a medicinal plant used in the treatment of various ailments.
Aida P. SĂRĂCIN   +6 more
doaj   +1 more source

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