Results 41 to 50 of about 128,718 (308)

The habitability of a stagnant-lid Earth

, 2017
Plate tectonics is a fundamental component for the habitability of the Earth. Yet whether it is a recurrent feature of terrestrial bodies orbiting other stars or unique to the Earth is unknown.
Breuer, D., Godolt, M., Grenfell, J. L., Höning, D., Nikolaou, A., Plesa, A. -C., Ruedas, T., Spohn, T., Stracke, B., Tosi, N.   +9 more
core   +1 more source

Lanthanides extraction processes in molten fluoride media. Application to nuclear spent fuel reprocessing [PDF]

, 2009
This paper describes four techniques of extraction of lanthanides elements (Ln) from molten salts in the general frame of reprocessing nuclear wastes; One of them is chemical: the precipitation of Ln ions in insoluble compounds (oxides or oxifluorides);
Cassayre, Laurent, Chamelot, Pierre, Gibilaro, Mathieu, Massot, Laurent, Nourry, Christophe, Taxil, Pierre   +5 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Repacking Accelerates High‐Silica Melts Extraction: Insights From Microstructural Record and Numerical Modeling

Geophysical Research Letters
Repacking enhances crystal mush permeability, accelerating melt extraction. However, identifying microstructural records of repacking is challenging, creating a gap in quantifying its effect on magmatic reservoirs. We identified extracted melt (rhyolite)
Hou‐Bin Chen, Boda Liu, Wei‐Qiang Ji, Shao‐Hua Zhang, Kai Zhao, Fu‐Yuan Wu   +5 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Physics-guided spatiotemporal approach for melt pool size prediction in laser powder bed fusion

Virtual and Physical Prototyping
This study first proposes a physics-guided spatiotemporal graph. The melt pool temporal feature nodes and spatial feature nodes are extracted from melt pool images based on spatiotemporal correlations. These feature points are treated as graph nodes, and
Yangkun Mao, Xin Lin, Haihong Zhu, Kunpeng Zhu   +3 more
doaj   +1 more source

Fabrication of Aluminum Alloy with Open-Channel and Columnar Structures through a Ceramic Fiber Template Method

Metals, 2023
Aluminum alloys with open-channel and columnar structures were fabricated by casting the melt of aluminum alloys using a ceramic fiber template method. Stainless steel plates or wires coated with ceramic fibers impregnated by polyvinyl alcohol were used ...
Hideo Nakajima
doaj   +1 more source

Apparatus ad method for quiescent containerless processing of high temperature metals and alloys in low gravity [PDF]

, 1987
The electron bombardment furnace consists of two confinement grid sections which may be moved and separated from each other. Inside the bombardment furnace, a tungsten element is enclosed.
Lacy, Lewis L., Robinson, Michael B.
core   +1 more source

Adiabat_1ph: A new public front-end to the MELTS, pMELTS, and pHMELTS models [PDF]

, 2005
The program adiabat_1ph is a simple text-menu driver for subroutine versions of the algorithms MELTS, pMELTS, and pHMELTS [Asimow et al., 2004; Ghiorso et al., 2002; Ghiorso and Sack, 1995].
Asimow, Paul D., Smith, Paula M.
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source