Results 111 to 120 of about 279,876 (309)

Fossilized Melts in Mantle Wedge Peridotites

Scientific Reports, 2018
The shallow oxidized asthenosphere may contain a small fraction of potassic silicate melts that are enriched in incompatible trace elements and volatiles.
Kosuke Naemura, Takao Hirajima, Martin Svojtka, Ichiko Shimizu, Tsuyosi Iizuka   +4 more
doaj   +1 more source

(Table 8) Major element oxides of glasses in melt inclusions in a single plagioclase phenocryst from sample Gor-188

, 2012
(Table 8) Major element oxides of glasses in melt inclusions in a single plagioclase phenocryst from sample Gor ...
M G Gavrilenko (6968354), V B Naumov (6961553), Gavrilenko, M G, Kononkova, N N, Naumov, V B, M L Tolstykh (6968351), N N Kononkova (6960374), Ozerov, AYu, Tolstykh, M L, AYu Ozerov (6968357)   +9 more
core   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

(Tabel S5b) Plagioclase-hosted melt inclusions, host plagioclase composition adjacent to inclusion, and thermobarometry of melt inclusion - host mineral pairs

, 2018
(Tabel S5b) Plagioclase-hosted melt inclusions, host plagioclase composition adjacent to inclusion, and thermobarometry of melt inclusion - host mineral ...
Melanie Siegburg (6968786), Bach, Wolfgang, Rocholl, Alexander, Wolfgang Bach (6960488), Klügel, Andreas, Alexander Rocholl (5480873), Siegburg, Melanie, Andreas Klügel (6968789)   +7 more
core   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

(Tabel S5a) Clinopyroxene-hosted melt inclusions, host clinopyroxene composition adjacent to inclusion, and thermobarometry of melt inclusion - host mineral pairs

, 2018
(Tabel S5a) Clinopyroxene-hosted melt inclusions, host clinopyroxene composition adjacent to inclusion, and thermobarometry of melt inclusion - host mineral ...
Melanie Siegburg (6968786), Bach, Wolfgang, Rocholl, Alexander, Wolfgang Bach (6960488), Klügel, Andreas, Alexander Rocholl (5480873), Siegburg, Melanie, Andreas Klügel (6968789)   +7 more
core   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Magmatic Storage and Volatile Fluxes of the 2021 La Palma Eruption

Geochemistry, Geophysics, Geosystems
The 2021 La Palma eruption (Tajogaite) was unprecedented in magnitude, duration, and degree of monitoring compared to historical volcanism on La Palma.
K. Dayton, E. Gazel, P. E. Wieser, V. R. Troll, J. C. Carracedo, M. Aulinas, F. J. Perez‐Torrado   +6 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source