Results 31 to 40 of about 40,904 (265)

Two enigmatic ridges in the Pantelleria Vecchia Bank (NW Sicilian Channel)

open access: yesHeliyon, 2023
The Pantelleria Vecchia Bank is a submerged calcareous-arenitic shoal in the NW sector of the Sicilian Channel. Together with other morphological heights, some of which are volcanic in origin, this shoal punctuates the shallow Adventure Plateau, which ...
Emanuele Lodolo   +3 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Melting–Recrystallization of Block Copolymer Crystals in Confined Environments [PDF]

open access: yesPolymer Journal, 2005
Recently crystallization of block copolymers in confined domains has been extensively studied. Crystallization in confined environments is usually initiated by homogeneous nucleation at large supercooling. Thus the crystals formed are highly imperfect and have lower crystallinity, compared with the crystals formed under normal crystallization ...
Xu, Jun-Ting   +3 more
openaire   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Effect of Geometrical Confinement on Ordering of Thermoplastic Polyurethanes with Crystallizable Hard and Soft Blocks

open access: yesCrystals, 2023
A series of multi-block thermoplastic polyurethanes incorporating different soft block structures was synthesized. This was achieved using a poly(butylene adipate) oligomer combined with its macrodiols of both an aromatic and aliphatic nature.
Ainur F. Abukaev   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

The Influence of Ocean Swell and Wind Waves on Iceberg Melting

open access: yesGeophysical Research Letters
Free‐floating icebergs are important sources of cold freshwater to the polar oceans, influencing both ocean circulation and climate. The influence of ubiquitous oscillatory flows, like those resulting from local wind‐driven waves and swells, on melting ...
James K. Sweetman   +2 more
doaj   +1 more source

Tourism, Design and Climate Change: The Urban Glaciology Experiment at Fuorisalone 2024 Event

open access: yesTourism and Hospitality
Glacier retreat due to climate change is accelerating worldwide, yet the phenomenon remains abstract for many people, especially those unfamiliar with mountain environments.
Antonella Senese   +6 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

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