Results 61 to 70 of about 40,904 (265)
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Room-temperature-cured MoSi2-phosphate emissivity coating with a self-sealing structure
While emissivity coatings on thermal insulation materials in aircrafts can help radiate aerodynamic heat flux, traditional high-temperature sintering oxidizes emissive agents, thereby degrading their emissive properties.
Xianqi Cao +11 more
doaj +1 more source
Polylactic acid (PLA) was melt-blended with Pinus radiata unmodified and modified (hydroxypropyled) bark polyflavonoids in order to use such polyphenolic building-blocks as functional additives for envisaged applications.
D. E. Garcia +5 more
doaj +1 more source
This paper reports on the effect of a TiN spray coating on aluminum to improve laser welding issues such as cracking susceptibility and laser absorption.
Sangwoo Nam, In-Ho Jung, Young-Min Kim
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Application of the used railway brake blocks in production of high-duty cast iron
Тhe problem refining of the used brake blocks of passenger cars is examined. There is shown possibility of production of high-test cast iron with a nodular graphite using charging materials with a high content of detrimental impurities.
D. A. Khudokormov +3 more
doaj
Analysis of SEPT9 Gene Promoter Methylation Status in Esophageal Squamous Cell Carcinoma
Introduction: The changes in the level of SEPT9 gene promoter methylation can contribute to the formation of esophageal squamous cell carcinoma. The aim of this study was to evaluate the level of changes in the level of SEPT9 gene promoter methylation in
Aida Mirza Aghasi, Saied Ghorbian
doaj
Reflection of sequence of geodynamic processes in geological structure of the Bug area
The age of formations composing granulite blocks of the Ukrainian Shield is a pro-blem for disputes. In order to ascertain the primary genesis and conditions of transduction of the Bug area rocks it is proposed to find out how was deep process realized ...
O. V. Usenko
doaj +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Multiblock thermoplastic polyurethane elastomers based on random and triblock copolymers were synthesized and studied. Dihydroxyl-terminated random copolymers were prepared by ring opening copolymerization of ε-caprolactone (CL) and 1,3-trimethylene
doaj +1 more source

